Diltiazem Impurity 7 CAS 84903-82-2
| CAS No. | 84903-82-2 |
| Molecular Formula | C19H22N2O3S |
| Molecular Weight | 358.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Diltiazem Impurity 7 (CAS 84903-82-2), a pharmacopoeial impurity reference standard (molecular formula C19H22N2O3S, MW 358.45 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Diltiazem Impurity 7 (C19H22N2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H22N2O3S |
| Molecular Weight | 358.45 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Diltiazem Standards
- Diltiazem Impurity 11 (CAS 81353-09-5)
- Diltiazem Impurity 24 (CAS CATO-C4X-136824)
- Diltiazem Impurity 26 (CAS 2055466-64-1)
- Diltiazem EP Impurity B (CAS 87447-47-0)
- Diltiazem Impurity 15 (CAS CATO-C4X-136815)
- Diltiazem impurity 29 (CAS 30193-56-7)
- Diltiazem Impurity 32 (CAS CATO-C4X-136832)
- Diltiazem Impurity 7 (CAS CATO-C4X-13687)
Recommended Standards
- N-Demethyldeacetyl Diltiazem (CAS 86408-44-8)
- Ethyl 4-(cyclohexylsulfanyl)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate (CAS 339031-39-9)
- Butyl 4-({[(4-aminophenyl)thio]acetyl}amino)-benzoate (CAS 913247-25-3)
- N-((1-Ethylpyrrolidin-2-yl)methyl)-2,4,5-trimethoxybenzenesulfonamide (CAS 88301-69-3)
- Dapagliflozin Impurity 76 (CAS 604-69-3)
- Norethisterone Acetate EP Impurity C (CAS 1175129-26-6)
- Levocabastine EP Impurity F (CAS 793621-70-2)
- (3-Methyl-5-(trifluoromethoxy)phenyl)methanol (CAS 916420-54-7)
- Fosfomycin Impurity 58 (CAS CATO-C4X-131658)
- 7-Chloro-6-methoxy-2,3-dihydro-1H-pyrrolo[2,3-b]quinoline (CAS 1266692-46-9)
- Mianserin Impurity 116 (CAS 142643-19-4)
- 3-(5-(2-Nitrophenyl)furan-2-yl)acrylic acid (CAS 58110-36-4)
- 4-Ethylbenzenecarbothioamide 4-Ethylthiobenzamide 57774-76-2 (CAS 57774-76-2)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com