Bisoprolol EP Impurity K CAS 864544-37-6
| CAS No. | 864544-37-6 |
| Molecular Formula | C18H29NO5 |
| Molecular Weight | 339.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 339.43 g/mol gives Bisoprolol EP Impurity K distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Bisoprolol EP Impurity K (CAS 864544-37-6, C18H29NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Bisoprolol EP Impurity K (C18H29NO5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bisoprolol EP Impurity K meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H29NO5 |
| Molecular Weight | 339.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Bisoprolol Standards
- Bisoprolol Impurity 115 (CAS CATO-C4X-1247115)
- Bisoprolol Impurity 92 (CAS CATO-C4X-124792)
- Bisoprolol Impurity 34 (CAS CATO-C4X-124734)
- Bisoprolol Impurity 114 (CAS CATO-C4X-1247114)
- Bisoprolol Impurity 116 (CAS CATO-C4X-1247116)
- Bisoprolol Impurity 71 (CAS CATO-C4X-124771)
- Bisoprolol Impurity 72 (CAS 2999705-55-2)
- Bisoprolol Impurity 76 (CAS CATO-C4X-124776)
Recommended Standards
- Salbutamol Impurity 124 (CAS CATO-C4X-1176124)
- Esomeprazole impurity 133 (CAS CATO-C4X-1112133)
- Ibuprofen Impurity 84 (CAS CATO-C4X-108284)
- Nalmefene impurity 20 (CAS 738552-29-9)
- Ibrutinib Impurity 169 (CAS CATO-C4X-1064169)
- Torasemide Impurity 11 (CAS 113844-99-8)
- Nintedanib Impurity 176 (CAS CATO-C4X-1814176)
- 2-Chloro-4-(2-chloro-4-methylphenyl)benzonitrile (CAS 1355247-42-5)
- 2-(6-Chloro-2-fluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628684-12-7)
- tert-Butyl N-(5-bromothiophen-2-yl)carbamate (CAS 943321-89-9)
- 2-Methyl-1H-benzo[d]imidazole-5-carbonitrile (CAS 92443-13-5)
- 2-(4-Phenylthiazol-2-yl)ethan-1-amine (CAS 61887-92-1)
- 3,3,4,4,5,5,5-Heptafluoropentyne (CAS 80337-25-3)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com