Nalmefene impurity 20 CAS 738552-29-9
| CAS No. | 738552-29-9 |
| Molecular Formula | C21H25NO3 |
| Molecular Weight | 339.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Nalmefene impurity 20 (CAS 738552-29-9, C21H25NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C21H25NO3, Nalmefene impurity 20 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 339.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H25NO3 |
| Molecular Weight | 339.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Related Nalmefene Standards
- Nalmefene Impurity 27 (CAS CATO-C4X-126827)
- Nalmefene Impurity 5 (CAS CATO-C4X-12685)
- Nalmefene (CAS 55096-26-9)
- Nalmefene Impurity 22 (CAS CATO-C4X-126822)
- Nalmefene Impurity 28 (CAS CATO-C4X-126828)
- Nalmefene Impurity 9 (CAS CATO-C4X-12689)
- Nalmefene Impurity N5 (CAS 91598-83-3)
- Nalmefene Impurity 14 (CAS CATO-C4X-126814)
Recommended Standards
- Bisoprolol Impurity 92 (CAS CATO-C4X-124792)
- Bisoprolol Impurity 115 (CAS CATO-C4X-1247115)
- Bisoprolol EP Impurity K (CAS 864544-37-6)
- Gabapentin Impurity 23 (CAS CATO-C4X-165423)
- Hyoscine EP Impurity A (CAS 4684-28-0)
- Flumazenil EP Impurity E (CAS 78756-03-3)
- Indacaterol Impurity 86 (CAS CATO-C4X-150086)
- (S)-3-((tert-Butoxycarbonyl)amino)-2-(pyridin-2-ylmethyl)propanoic acid (CAS 1240588-75-3)
- N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine-1-carboxamide (CAS 874290-96-7)
- 2-((Trifluoromethyl)sulfonyl)acetic acid (CAS 1067-00-1)
- 1-((3-Isopropyl-1,2,4-oxadiazol-5-yl)methyl)-1H-pyrazole-4-carboxylic acid (CAS 1270773-81-3)
- 4-Aminomethyl-7-azaindole, 97% (CAS 888498-07-5)
- Methyl 3-bromoisoxazole-4-carboxylate (CAS 1447958-01-1)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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