4-(3-(Trifluoromethyl)phenyl)pyrimidin-2-amine CAS 866019-76-3
| CAS No. | 866019-76-3 |
| Molecular Formula | C11H8F3N3 |
| Molecular Weight | 239.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-(3-(Trifluoromethyl)phenyl)pyrimidin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-(3-(Trifluoromethyl)phenyl)pyrimidin-2-amine (CAS 866019-76-3) is a high-purity analytical reference standard with the molecular formula C11H8F3N3 and a molecular weight of 239.20 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 4-(3-(Trifluoromethyl)phenyl)pyrimidin-2-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 239.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H8F3N3 |
| Molecular Weight | 239.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 2-(4-(Trifluoromethyl)phenyl)pyrimidin-5-amine (CAS 1094311-67-7)
- 5-(4-(Trifluoromethyl)phenyl)pyrimidin-2-amine (CAS 1111104-89-2)
- 5-(2-(Trifluoromethyl)phenyl)pyrimidin-2-amine (CAS 1111105-09-9)
- 6-(4-(Trifluoromethyl)phenyl)pyrazin-2-amine (CAS 1159819-32-5)
- 6-(4-(Trifluoromethyl)phenyl)pyridazin-3-amine (CAS 1215073-83-8)
- 5-(Trifluoromethyl)-[2,3'-bipyridin]-5'-amine (CAS 1255634-59-3)
- 6-(3-(Trifluoromethyl)phenyl)pyrimidin-4-amine (CAS 1482437-88-6)
- 2-(3-(Trifluoromethyl)phenyl)pyrimidin-5-amine (CAS 827322-74-7)
Recommended Standards
- 3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[3,4-a]isoquinoline (CAS 35515-45-8)
- 4-(4-(Trifluoromethyl)phenyl)pyrimidin-2-amine (CAS 916792-24-0)
- 3-(Pyridin-3-yl)-5-(trifluoromethyl)pyridin-2-amine (CAS 902745-40-8)
- 5-(3-(Trifluoromethyl)phenyl)pyrimidin-2-amine (CAS 947592-40-7)
- 1-(Dimethylamino)-3-phenylpropan-2-one (CAS 114049-98-8)
- Benzyl 4-((2-amino-N-isopropylacetamido)methyl)piperidine-1-carboxylate (CAS 1353943-98-2)
- 2-(3-(Tert-butyl)-5,9-dimethyl-7-oxo-7h-furo[3,2-g]chromen-6-yl)acetic acid (CAS 664366-06-7)
- Methyl 3-(piperidin-4-ylamino)benzoate (CAS 1184623-74-2)
- 1-piperidin-4-yl-1H-benzimidazole,HCl (CAS 83763-11-5)
- [(Anthracen-9-yl)methyl](propan-2-yl)amine (CAS 444576-95-8)
- 4-Bromo-2,3,5,6-tetramethylbenzoic acid (CAS 3360-64-3)
- Diethyl 2-(((1H-indazol-6-yl)amino)methylene)malonate (CAS 65642-21-9)
- 5-Chloro-4-((3,4-dichlorophenoxy)methyl)-2-fluoro-N-(methylsulfonyl)benzamide (CAS 1355631-24-1)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com