N-(4-Chloro-2-methylphenyl)-4-(2-{[(4-chloro-2-methylphenyl)carbamothioyl]amino}ethyl)piperazine-1-carbothioamide CAS 866038-37-1
| CAS No. | 866038-37-1 |
| Molecular Formula | C22H27Cl2N5S2 |
| Molecular Weight | 496.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-Chloro-2-methylphenyl)-4-(2-{[(4-chloro-2-methylphenyl)carbamothioyl]amino}ethyl)piperazine-1-carbothioamide (CAS 866038-37-1) is a high-purity analytical reference standard with the molecular formula C22H27Cl2N5S2 and a molecular weight of 496.52 g/mol.
The molecular framework of N-(4-Chloro-2-methylphenyl)-4-(2-{[(4-chloro-2-methylphenyl)carbamothioyl]amino}ethyl)piperazine-1-carbothioamide (C22H27Cl2N5S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(4-Chloro-2-methylphenyl)-4-(2-{[(4-chloro-2-methylphenyl)carbamothioyl]amino}ethyl)piperazine-1-carbothioamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27Cl2N5S2 |
| Molecular Weight | 496.52 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
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Recommended Standards
- (2-((4-((4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)amino)-4-methyl-4,5-dihydrooxazol-4-yl)methanol (CAS 937263-81-5)
- Cefoperazone Impurity 65 (CAS CATO-C4X-114965)
- 1,8-(Diphenylphosphino)naphthalene (CAS 153725-04-3)
- Silodosin Impurity 29 (CAS 1431373-77-1)
- Boc-DL-Ser(Me)-OH.DCHA (CAS 95105-33-2)
- Methyl 7-amino-2,3-dihydrobenzofuran-2-carboxylate (CAS 847948-99-6)
- [S(R)]-N-[(R)-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]phenylmethyl]-N,2-dimethyl-2-propanesulfinamide (CAS 2757083-09-1)
- 3-Iodoimidazo[1,2-a]pyrimidine-2-carboxylic acid (CAS 1823898-58-3)
- (1-Cyclopropylethyl)[(2,4-dimethoxyphenyl)methyl]amine (CAS 1155988-21-8)
- 1,3,5-Triisopropyl-2-nitrobenzene (CAS 13402-31-8)
- (S)-2-Amino-N-((S)-1-(((S)-4-chloro-3-oxo-1-phenylbutan-2-yl)amino)-1-oxopropan-2-yl)propanamide (CAS 102129-66-8)
- Methyl 5-acetylthiophene-2-carboxylate(Arotinolol Impurity 6) (CAS 4101-81-9)
- Methyl 3-formylbenzimidate hydrochloride (CAS 66739-94-4)
- Protein Kinase C? Peptide Substrate (CAS 120253-69-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com