1-(4-Methylphenyl)-3-[(morpholin-4-yl)methyl]-4-phenylazetidin-2-one CAS 866049-15-2
| CAS No. | 866049-15-2 |
| Molecular Formula | C21H24N2O2 |
| Molecular Weight | 336.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(4-Methylphenyl)-3-[(morpholin-4-yl)methyl]-4-phenylazetidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(4-Methylphenyl)-3-[(morpholin-4-yl)methyl]-4-phenylazetidin-2-one (CAS 866049-15-2), molecular formula C21H24N2O2 and molecular weight 336.43 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-Methylphenyl)-3-[(morpholin-4-yl)methyl]-4-phenylazetidin-2-one (C21H24N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C21H24N2O2 |
| Molecular Weight | 336.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Methylphenyl Standards
- 3-(4-Methylphenyl)-1-phenyl-1H,4H-indeno[1,2-c]pyrazol-4-one (CAS 1020252-53-2)
- N-(2-Methylphenyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine-1-carboxamide (CAS 833436-43-4)
- 2-{[(4-methylphenyl)methyl]amino}-2-phenyl-N-(1,3-thiazol-2-yl)acetamide (CAS 1031703-61-3)
- 1-[(4-Methylphenyl)methyl]-4-[5-(thiophen-2-yl)-1H-pyrazol-3-yl]piperidine (CAS 321848-33-3)
- Ethyl 3-(4-methylphenyl)-5-phenoxy-1,2,4-triazine-6-carboxylate (CAS 338965-89-2)
- Methyl 4-[(4-methylphenyl)sulfonyl]-3-nitrobenzenecarboxylate (CAS 477871-40-2)
- (4Z)-4-[(4-Methylphenyl)methylidene]-1,3-diphenyl-4,5-dihydro-1H-pyrazol-5-one (CAS 39143-16-3)
- 1-(4-Methylphenyl)-4-phenyl-3-[(piperidin-1-yl)methyl]azetidin-2-one (CAS 551921-50-7)
Recommended Standards
- 1-(4-Acetylphenyl)-N-benzylpiperidine-4-carboxamide (CAS 900018-96-4)
- 1-(6-(2-Hydroxy-3-(isopropylamino)propoxy)-7-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethanone (CAS 59839-39-3)
- 1-(2-(Benzo[d]thiazol-2-ylthio)acetyl)piperidine-4-carboxylic acid (CAS 784195-75-1)
- 1,1,2,2-Tetraphenylhydrazine (CAS 632-52-0)
- tert-Butyl 4-(dimethylphosphoryl)-3,6-dihydropyridine-1(2H)-carboxylate (CAS 2694789-06-3)
- 5-(O-tolylthio)pentan-2-one (CAS 1183995-09-6)
- 7-Chloro-2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-3-[(tetrahydro-2-furanyl)methyl]-4(3H)-quinazolinone (CAS 1057725-14-0)
- 5-Chloroisophthalaldehyde (CAS 105511-08-8)
- Ethyl 1-ethyl-1H-imidazole-2-carboxylate (CAS 62366-55-6)
- 2-pHenyl-2-(phenylsulfanyl)acetic acid (CAS 10490-07-0)
- 1-(2-Ethynylphenyl)cyclopropane-1-carboxylic acid (CAS 2229071-03-6)
- (S)-8-(3-fluorophenyl)-9a-phenyl-9,9a-dihydropyrido[1,2-a]indole-6,10-dione (CAS 2368851-44-7)
- Abiraterone Impurity 78 (CAS 98449-11-7)
- Acetyl Tetrapeptide-5 (CAS 820959-17-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com