1-[(3-Chloro-4-fluorophenyl)methyl]piperazine CAS 869947-16-0
| CAS No. | 869947-16-0 |
| Molecular Formula | C11H14ClFN2 |
| Molecular Weight | 228.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[(3-Chloro-4-fluorophenyl)methyl]piperazine (CAS 869947-16-0), molecular formula C11H14ClFN2 and molecular weight 228.69 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H14ClFN2, 1-[(3-Chloro-4-fluorophenyl)methyl]piperazine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 228.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14ClFN2 |
| Molecular Weight | 228.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-2-cyclohexylamino-3-fluoropyridine (CAS 1020253-24-0)
- 1-[(2-Chloro-4-fluorophenyl)methyl]piperazine (CAS 118630-33-4)
- (2-Chloro-6-fluorophenyl)(cyclopentyl)methanol (CAS 1225687-12-6)
- 1-[(3-Chloro-2-fluorophenyl)methyl]piperazine (CAS 1240565-18-7)
- 1-[(4-Chloro-3-fluorophenyl)methyl]piperazine (CAS 1240572-89-7)
- 1-(2-Chloro-4-fluorobenzyl)pyrrolidin-3-amine (CAS 1247243-31-7)
- 1-(5-Chloro-2-fluorobenzyl)piperazine (CAS 1251127-61-3)
- (3-Chloro-4-fluorophenyl)(cyclopentyl)methanol (CAS 1339640-22-0)
Recommended Standards
- 1-(4-Chloro-3-fluorophenyl)-2,2-dimethylbutan-1-one (CAS 898765-70-3)
- 2-Chloro-2,2-dimethyl-4-fluorobutyrophenone (CAS 898765-86-1)
- 1-(3-Chloro-4-fluorophenyl)-3,3-dimethylbutan-1-one (CAS 898764-66-4)
- 3-Chloro-2,2-dimethyl-4-fluorobutyrophenone (CAS 898765-72-5)
- 3-Amino-N-cyclohexyl-2-hydroxy-N-methylbenzamide (CAS 473731-12-3)
- Tetrahydro-N-methyl-2H-pyran-4-carboxamide (CAS 1017781-43-9)
- 11-Acetoxy-Δ9-tetrahydrocannabinol (CAS 26108-47-4)
- N-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-N'-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]thiourea (CAS 1173373-71-1)
- N-(Oxetan-3-ylidene)pivalamide (CAS 1632286-09-9)
- 4-((Dimethylamino)methyl)-3-methylisoxazol-5-amine (CAS 1869087-15-9)
- Benzyl 4-(3-azetidinyloxy)benzoate (CAS 1220038-81-2)
- Pyrazolo[1,5-a]pyridine-3-carbothioamide (CAS 885275-44-5)
- (E)-3-(6-methylpyridin-2-yl)acrylic acid (CAS 106988-32-3)
- D-[Ser]8-Semaglutide (CAS CATO-CPTD788632)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com