1-(3-Chloro-4-fluorophenyl)-3,3-dimethylbutan-1-one CAS 898764-66-4
| CAS No. | 898764-66-4 |
| Molecular Formula | C12H14ClFO |
| Molecular Weight | 228.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Chloro-4-fluorophenyl)-3,3-dimethylbutan-1-one (CAS 898764-66-4), molecular formula C12H14ClFO and molecular weight 228.69 g/mol, is a CATO reference standard with documented purity and traceability.
1-(3-Chloro-4-fluorophenyl)-3,3-dimethylbutan-1-one (C12H14ClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(3-Chloro-4-fluorophenyl)-3,3-dimethylbutan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14ClFO |
| Molecular Weight | 228.69 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
- 1-(2-Chloro-6-fluorobenzyl)piperazine (CAS 215655-20-2)
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- (6,6-Dimethyl-1,4-dioxan-2-yl)methanesulfonyl chloride (CAS 2138584-95-7)
- 1-[(3-Chloro-4-fluorophenyl)methyl]piperazine (CAS 869947-16-0)
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- 4-Amino-5-bromo-1-(3,4-difluorophenyl)pyrimidin-2(1H)-one (CAS 1416438-80-6)
- AR-C155858 (CAS 496791-37-8)
- (R)-tert-Butyl 3-((S)-2-amino-N,3-dimethylbutanamido)pyrrolidine-1-carboxylate (CAS 1401665-05-1)
- Tert-butyl 3-(pyridin-2-ylamino)azetidine-1-carboxylate (CAS 1389315-08-5)
- 6-Hydroxybenzofuran (CAS 13196-11-7)
- 2-Methyl-1,3,5-triphenylpentane-1,5-dione (CAS 10226-00-3)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
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