3,4-Difluoro-2-ethoxyphenylboronic acid CAS 1451391-69-7
| CAS No. | 1451391-69-7 |
| Molecular Formula | C8H9BF2O3 |
| Molecular Weight | 201.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3,4-Difluoro-2-ethoxyphenylboronic acid (CAS 1451391-69-7), molecular formula C8H9BF2O3 and molecular weight 201.96 g/mol, is a CATO reference standard with documented purity and traceability.
3,4-Difluoro-2-ethoxyphenylboronic acid (C8H9BF2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9BF2O3 |
| Molecular Weight | 201.96 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
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- 2,6-Difluoro-3-ethoxyphenylboronic acid (CAS 849062-00-6)
- 3,5-Difluoro-4-methoxy-2-methylphenylboronic acid (CAS 2096338-65-5)
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Recommended Standards
- (4-Ethoxy-2,6-difluorophenyl)boronic acid (CAS 1310403-94-1)
- (4-Ethoxy-2,5-difluorophenyl)boronic acid (CAS 1452575-83-5)
- (6-Ethoxy-2,3-difluorophenyl)boronic acid (CAS 1309980-95-7)
- (3-(Difluoromethyl)-4-methoxyphenyl)boronic acid (CAS 1704065-70-2)
- 2-Bromo-4-chloro-6-ethynylpyridine (CAS 1256820-09-3)
- Rhapontisterone (CAS 137476-71-2)
- 6-(3-Fluorophenyl)imidazo[2,1-b]thiazol-5-amine (CAS 1432681-04-3)
- tert-Butyl 3-formylthiophene-2-carboxylate (CAS 1379369-59-1)
- 3,4-Dichlorobenzyl Chloride (CAS 102-47-6)
- 2-[4-(trifluoromethyl)pyridin-2-yl]ethan-1-amine hydrochloride (CAS 1803607-61-5)
- 3-(4-Amino-1H-pyrazol-1-yl)-2-methylpropane-1,2-diol (CAS 2433769-41-4)
- N,N-Dimethyl-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-sulfonamide (CAS 478077-48-4)
- 3-(2,2-Dimethylpropanamido)propanoic acid (CAS 5910-56-5)
- Eosinophilotactic Peptide (CAS 61756-28-3)
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