Atomoxetine EP Impurity A HCl CAS 873310-33-9
| CAS No. | 873310-33-9 |
| Molecular Formula | C16H19NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Atomoxetine EP Impurity A HCl.
CATO supplies Atomoxetine EP Impurity A HCl (CAS 873310-33-9), a pharmacopoeial impurity reference standard (molecular formula C16H19NOHCl, MW 277.79 g/mol) used for the identification and quantification of trace impurities in APIs.
Atomoxetine EP Impurity A HCl (C16H19NOHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H19NO HCl |
| Molecular Weight | 277.79 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Atomoxetine Standards
- Atomoxetine Impurity 50 (CAS 1007832-68-9)
- Atomoxetine impurity 40 (CAS 1010818-92-4)
- Atomoxetine impurity 41 (CAS 1010818-92-4（free base）)
- Atomoxetine EP Impurity C (CAS 1010818-96-8)
- Atomoxetine Impurity 9 HCl (CAS 1011-59-2)
- Atomoxetine EP impurity B (CAS 105314-53-2)
- Atomoxetine impurity 01 (CAS 109306-10-7)
- Atomoxetine EP Impurity H (S-Isomer) (CAS 114133-37-8)
Recommended Standards
- Atorvastatin Oxirane Impurity (CAS 1246818-88-1)
- Dobutamine Impurity 8 (CAS 14165-67-4)
- Tizanidine Impurity 67 (CAS 67357-56-6)
- Pazopanib Impurity 51 (CAS CATO-C4X-172551)
- Ethyl 2-iodo-5-nitrobenzoate (CAS 835916-53-5)
- 1-(3-Bromobut-3-en-1-yl)-2-methoxybenzene (CAS 731773-15-2)
- 3-(4-Methoxyphenyl)-5-nitro-1H-indazole (CAS 395099-28-2)
- Methyl 2-Acetoxy-4-bromobutanoate (CAS 76799-57-0)
- 4,9-Dibromo-6,7-diphenyl-[1,2,5]thiadiazolo[3,4-g]quinoxaline (CAS 1262727-09-2)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
Why CATO?
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