Atorvastatin Oxirane Impurity CAS 1246818-88-1
| CAS No. | 1246818-88-1 |
| Molecular Formula | C26H24FNO3 |
| Molecular Weight | 417.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Atorvastatin Oxirane Impurity (C26H24FNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Atorvastatin Oxirane Impurity (CAS 1246818-88-1), a pharmacopoeial impurity reference standard (molecular formula C26H24FNO3, MW 417.47 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H24FNO3 |
| Molecular Weight | 417.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Atorvastatin Standards
- Atorvastatin Impurity 103 (CAS 1797905-42-0)
- Atorvastatin Impurity 82 (CAS 125971-96-2)
- Atorvastatin Impurity 154 (CAS 1331869-19-2)
- Atorvastatin Impurity 104 (CAS CATO-C4X-1132104)
- Atorvastatin EP Impurity D (CAS 148146-51-4)
- Atorvastatin Impurity 145 (CAS CATO-C4X-1132145)
- Atorvastatin Impurity 27 (CAS 693793-82-7)
- Atorvastatin Impurity 26 (CAS 444577-70-2)
Recommended Standards
- Citalopram Impurity 96 (CAS CATO-C4X-110996)
- (R)-2-(((Benzyloxy)carbonyl)amino)-1-((S)-2,5-dihydrofuran-2-yl)ethyl 4-methylbenzenesulfonate (CAS 1001547-78-9)
- Citalopram Impurity 95 (CAS CATO-C4X-110995)
- 2-hydroxy-S-(4-{6-[(oxan-4-yl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethane-1-sulfonamido (CAS 1012345-91-3)
- Trelagliptin Impurity 54 (CAS 1261686-95-6)
- Valsartan Impurity 116 (CAS CATO-C4X-1057116)
- Telmisartan Impurity 99 (CAS CATO-C4X-135999)
- 6-(4-Fluorophenyl)-1,4-dimethyl-9H-carbazole (CAS 882747-34-4)
- Acetylated Penicilloic Acid Disodium Salt (CAS CATO-C3D-263263)
- Diacerein Impurity 25 (CAS CATO-C4X-108125)
- 5-Allyl-2-mercapto-4,6-dimethylnicotinonitrile (CAS 186337-14-4)
- Fmoc-3,4-difluoro-L-phenylalanine (CAS 198560-43-9)
- Moxifloxacin Impurity 66 (CAS 38233-47-5)
- D-Phe22-Tirzepatide (CAS CATO-CPTD788912)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com