2-(Piperazin-1-yl)nicotinamide dihydrochloride CAS 87394-52-3
| CAS No. | 87394-52-3 |
| Molecular Formula | C10H14N4O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Piperazin-1-yl)nicotinamide dihydrochloride.
2-(Piperazin-1-yl)nicotinamide dihydrochloride (CAS 87394-52-3) is a high-purity analytical reference standard with the molecular formula C10H14N4OHCl and a molecular weight of 242.71 g/mol.
The molecular framework of 2-(Piperazin-1-yl)nicotinamide dihydrochloride (C10H14N4OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Piperazin-1-yl)nicotinamide dihydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H14N4O 2*HCl |
| Molecular Weight | 242.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- 1-Ethyl-8-methylquinolin-4(1H)-one (CAS 1211201-30-7)
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- [1,2,4]Triazolo[4,3-b]pyridazin-3-ylmethanol (CAS 88277-73-0)
- 1-(Thiazolo[5,4-b]pyridin-2-yl)piperidine-3-carboxylic acid (CAS 950312-57-9)
- 2-Bromo-3-chloro-6-hydroxybenzonitrile (CAS 1934463-16-7)
- (5-Bromopyrimidin-4-yl)(phenyl)methanol (CAS 69927-45-3)
- Ethyl 2-(trifluoromethyl)piperazine-1-carboxylate (CAS 1123515-55-8)
- 6-Acetylacteoside (CAS 441769-43-3)
- Sertraline EP Impurity G (CAS 79617-98-4)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com