Sertraline EP Impurity G CAS 79617-98-4
| CAS No. | 79617-98-4 |
| Molecular Formula | C17H17Cl2N |
| Molecular Weight | 306.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sertraline EP Impurity G is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Sertraline EP Impurity G (CAS 79617-98-4) is a certified pharmaceutical impurity reference standard with the molecular formula C17H17Cl2N and a molecular weight of 306.23 g/mol.
Structurally, Sertraline EP Impurity G (C17H17Cl2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 306.23 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sertraline EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17Cl2N |
| Molecular Weight | 306.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sertraline Standards
- Sertraline Impurity C49 (CAS 140631-53-4)
- Sertraline Impurity 53 (CAS 2184053-08-3)
- Sertraline (CAS 79617-96-2)
- Sertraline EP Impurity A (CAS 79836-45-6)
- Sertraline oxime Impurity (CAS 152642-35-8)
- Sertraline Impurity 64 (CAS 79560-20-6)
- Sertraline Impurity 51 (CAS CATO-C4X-134451)
- Sertraline-13C-15N-d3 (CAS CATO-C4X-13449)
Recommended Standards
- Methyl 4-((3,4-dinitro-1h-pyrazol-1-yl)methyl)benzoate (CAS 313062-84-9)
- 3475-74-9 N-(4-Dimethylamino-3,5-dinitrophenyl)maleimide 1-(4-(Dimethylamino)-3,5-dinitrophenyl)-1H-pyrrole-2,5-dione Maleimide, N-(4-(dimethylamino)-3,5-dinitrophenyl)- 1H-Pyrrole-2,5-dione, 1-(4-(dimethylamino)-3,5-dinitrophenyl)- 4-21-00-04641 (Beilstein Handbook Reference) AI3-62630 BRN 0333082 N-(4-Dimethylamino-3,5-dinitrophenyl)-maleimide EINECS 222-449-3 NSC 90450 (CAS 3475-74-9)
- Ethyl 4-nitro-1-(4-nitrophenyl)-1H-pyrazole-3-carboxylate (CAS 21443-85-6)
- Blonanserin Impurity 23 (CAS CATO-C4X-111023)
- Enrofloxacin Impurity 9 (CAS CATO-C4X-16289)
- Trametinib impurity 9 (CAS 29632-74-4)
- Voriconazole Impurity 76 HCl (CAS 188416-20-8)
- 2-Bromo-4-tert-butyl-1-methoxybenzene (CAS 41280-65-3)
- 5-(NAPHTHALEN-1-YL)FURAN-2(3H)-ONE (CAS 906560-16-5)
- tert-Butyl ((6-bromo-4-formylpyridin-2-yl)methyl)carbamate (CAS 1393568-38-1)
- Atracurium EP Impurity G (CAS 1699-51-0)
- 5-(2,6-Dichlorophenyl)furan-2-carbaldehyde (CAS 94078-34-9)
- (R)-1-((R)-3-Methoxypyrrolidin-1-yl)propan-2-ol (CAS 2158298-27-0)
- 98035-79-1 Small cardioactive peptide A L-Methioninamide, L-alanyl-L-arginyl-L-prolylglycyl-L-tyrosyl-L-leucyl-L-alanyl-L-phenylalanyl-L-prolyl-L-arginyl- SCPA (CAS 98035-79-1)
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