1-{3-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]propyl}piperazine CAS 874754-27-5
| CAS No. | 874754-27-5 |
| Molecular Formula | C13H18N4OS |
| Molecular Weight | 278.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-{3-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]propyl}piperazine (CAS 874754-27-5), molecular formula C13H18N4OS and molecular weight 278.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-{3-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]propyl}piperazine (C13H18N4OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-{3-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]propyl}piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H18N4OS |
| Molecular Weight | 278.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 1-Methyl-3,5-diphenylpyridazine-4(1H)-thione (CAS 59617-88-8)
- (E)-2-(4-Chlorobenzylidene)-5-oxopyrazolidin-2-ium-1-ide (CAS 1164115-67-6)
- 1-(4-Bromo-2-(trifluoromethyl)phenyl)-3,3-difluoropyrrolidine (CAS 1774895-87-2)
- ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol succinate (CAS 168146-84-7)
- methyl 3-(1-ethyl-1H-pyrazol-4-yl)but-2-enoate (CAS 1563994-30-8)
- 5-Amino-2-fluoro-4-hydroxybenzonitrile (CAS 388091-38-1)
- 1,4-Bis(3-fluorobenzyl)-1,4-diazepane (CAS 1261235-23-7)
- 6-(4-Fluorobenzyl)-3-(p-tolylamino)-1,2,4-triazin-5(4H)-one (CAS 899943-25-0)
- 2-(Cyclopropylmethyl)-5-hydroxybenzonitrile (CAS 1243411-09-7)
- [3-(difluoromethoxy)phenyl]boronic acid (CAS 866607-09-2)
- Calcium-Like Peptide 3 (CAS 261969-05-5)
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