2-Bromo-4,5-difluorobenzenesulfonamide CAS 874801-45-3
| CAS No. | 874801-45-3 |
| Molecular Formula | C6H4BrF2NO2S |
| Molecular Weight | 272.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Bromo-4,5-difluorobenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Bromo-4,5-difluorobenzenesulfonamide (CAS 874801-45-3), a certified reference material (molecular formula C6H4BrF2NO2S, MW 272.07 g/mol) for analytical method development and quality control.
The molecular framework of 2-Bromo-4,5-difluorobenzenesulfonamide (C6H4BrF2NO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H4BrF2NO2S |
| Molecular Weight | 272.07 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
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- 4-Bromo-2,3-difluorobenzenesulfonamide (CAS 1133123-01-9)
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Recommended Standards
- 2-(4-(Difluoromethyl)-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2410032-62-9)
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- 2-(3-(Difluoromethyl)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 627526-04-9)
- 3-(4-Bromo-2-fluorophenyl)-2-cyanopropionic Acid (CAS 2044707-14-2)
- 5-Methyl-7-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 478041-01-9)
- H-Arg-4MβNA (CAS 60285-94-1)
- (2-Bromophenyl)(5-chloro-2-methoxyphenyl)methanol (CAS 1443331-41-6)
- Paclitaxel Impurity 32 (Baccatin VI) (CAS 57672-79-4)
- Ambroxol Impurity 59 (CAS 2376577-10-3)
- 4-Amino-N-cyclohexyl-1-ethyl-1h-pyrazole-3-carboxamide (CAS 895930-35-5)
- n-(4-Fluorophenyl)-2-(p-tolyl)thiazole-4-carboxamide (CAS 400079-13-2)
- 1-Benzyl-4-(3-bromo-2-(trifluoromethyl)-phenyl)piperazine (CAS 1707392-14-0)
- (S)-1-Boc-2-Propylpiperazine (CAS 888972-67-6)
- Dulaglutide (CAS 923950-08-7)
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