Axitinib Impurity 88 CAS 87511-99-7
| CAS No. | 87511-99-7 |
| Molecular Formula | C10H15NO2 |
| Molecular Weight | 181.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Axitinib Impurity 88.
CATO supplies Axitinib Impurity 88 (CAS 87511-99-7), a pharmacopoeial impurity reference standard (molecular formula C10H15NO2, MW 181.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Axitinib Impurity 88 (C10H15NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H15NO2 |
| Molecular Weight | 181.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 1 |
Related Axitinib Standards
- Axitinib Impurity 85 (CAS 13959-26-7)
- Axitinib Impurity N27 (CAS 20877-02-5)
- Axitinib Impurity 17 (CAS CATO-C4X-107117)
- Axitinib Impurity 17 (CAS 20054-45-9)
- Axitinib Impurity 13 (CAS 2527-66-4)
- Axitinib Impurity N22 (CAS 7597-18-4)
- Axitinib Impurity 37 (CAS CATO-C4X-107137)
- Axitinib Impurity 66 (CAS 2419145-29-0)
Recommended Standards
- Omeprazole Impurity 60 (CAS 150054-47-0)
- 2-(2,6-Dimethoxyphenyl)ethan-1-amine (CAS 486-95-3)
- Tamsulosin EP Impurity F (CAS 6781-17-5)
- 2-(2,3-dimethoxyphenyl)ethan-1-amine (CAS 3213-29-4)
- Venlafaxine Impurity 39 (CAS 93413-46-8)
- Azelnidipine Impurity 3 (CAS 170749-59-4)
- Nicardipine Impurity 48 (CAS CATO-C4X-171048)
- Furfuryl Acetate (CAS 623-17-6)
- N-(Aminoethyl)-5-naphthylamine-1-sulfonic Acid (CAS 50402-56-7)
- N-(4-fluorobenzyl)-4-(3-methylbutanoyl)-1H-pyrrole-2-carboxamide (CAS 478259-39-1)
- 4-(3,4,5-Trimethyl-1h-pyrazol-1-yl)phenol (CAS 1343949-48-3)
- (R)-Ethyl 2-amino-3-(7-methoxy-1-methyl-1H-indol-3-yl)propanoate (CAS 655239-35-3)
- 4-(Cyclopropylamino)piperidine-4-carboxamide (CAS 1173146-01-4)
- His-Aib-Semaglutide (CAS CATO-C4X-2226220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com