Terbinafine EP Impurity C HCI CAS 877265-30-0
| CAS No. | 877265-30-0 |
| Molecular Formula | C21H25N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Terbinafine EP Impurity C HCI (CAS 877265-30-0), a pharmacopoeial impurity reference standard (molecular formula C21H25NHCl, MW 327.90 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Terbinafine EP Impurity C HCI is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 327.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H25N HCl |
| Molecular Weight | 327.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Terbinafine Standards
- Terbinafine Hydroxy Benzoate (CAS 1076198-30-5)
- Terbinafine Carboxylic Acid Methyl Ester (Oxalate) (CAS 1076199-76-2)
- Terbinafine Impurity 4 (Mixture of Z and E Isomers) (CAS 114311-70-5)
- Terbinafine Impurity 5-d7 (CAS 1185238-58-7)
- Terbinafine-d7 Hydrochloride (CAS 1185240-27-0)
- Terbinafine Impurity 4 (CAS 125660-64-2)
- Terbinafine Impurity 10 (CAS 126764-17-8)
- Terbinafine-d3 HCl (N-methyl-d3) (CAS 1310012-15-7)
Recommended Standards
- Eldecalcitol Impurity 40 (CAS 1217549-29-5)
- Azilsartan impurity 149 (CAS CATO-C4X-1096149)
- N-Nitroso Midazolam EP Impurity J (CAS CATO-C4X-150939)
- 4-Benzyl-5-(3,4-dimethoxyphenyl)-4H-1,2,4-triazole-3-thiol (CAS 299921-16-7)
- Cobalt, dicarbonyl(diphenylphosphinothioito-P,S)(tricyclohexylphosphine)-, (TB-5-23)- (CAS 112792-50-4)
- 1-[1-(4-bromophenyl)ethyl]piperazine (CAS 512164-44-2)
- 2-Amino-5-benzyl-5-(thiophen-2-yl)-4,5-dihydro-1H-imidazol-4-one (CAS 1354938-08-1)
- 1-(4-Fluorophenoxy)cyclopropane-1-carboxylic acid (CAS 1399657-46-5)
- Iomeprol Impurity 13 (CAS CATO-C4X-182013)
- Semaglutide Impurity 6 (CAS 62-57-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com