6-(chloromethyl)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran CAS 877977-41-8

Purity 97%+In StockPharmaceutical Standards
CAS No.877977-41-8
Molecular FormulaC12H15ClO2
Molecular Weight226.70 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(chloromethyl)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran CAS 877977-41-8 chemical structure

Description

The occurrence of 6-(chloromethyl)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-(chloromethyl)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran (CAS 877977-41-8) is a high-purity analytical reference standard with the molecular formula C12H15ClO2 and a molecular weight of 226.70 g/mol.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 6-(chloromethyl)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 6-(chloromethyl)-5-ethoxy-2-methyl-2,3-dihydro-1-benzofuran meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H15ClO2
Molecular Weight226.70 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing

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