Iodohippurate Dihydrate For Radiopharmaceutical Preparations EP Impurity A CAS 88-67-5
| CAS No. | 88-67-5 |
| Molecular Formula | C7H5IO2 |
| Molecular Weight | 248.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Iodohippurate Dihydrate For Radiopharmaceutical Preparations EP Impurity A (CAS 88-67-5), a pharmacopoeial impurity reference standard (molecular formula C7H5IO2, MW 248.02 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system, Iodohippurate Dihydrate For Radiopharmaceutical Preparations EP Impurity A is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 248.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Iodohippurate Dihydrate For Radiopharmaceutical Preparations EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5IO2 |
| Molecular Weight | 248.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | I-containing |
Related Iodohippurate Standards
Recommended Standards
- 7-Bromo-4,5-difluoroindolin-2-one (CAS 2090777-89-0)
- 4-Iodobenzoic Acid (CAS 619-58-9)
- 6-Iodopicolinamide (CAS 851102-42-6)
- 4-Hydroxy-3-iodobenzaldehyde (CAS 60032-63-5)
- Oxytetracycline EP Impurity B Hydrate (CAS 305833-60-7)
- Baloxavir Impurity 103 (CAS 2762066-96-4)
- Malic Acid Impurity 3 (CAS 66178-02-7)
- 8-Chloro-2,3,4,9-tetrahydro-1h-carbazol-1-amine (CAS 1042626-75-4)
- 1-Methyl-3-[3-(trifluoromethyl)phenoxy]-1,2-dihydroquinoxalin-2-one (CAS 338774-65-5)
- 4-(3,3-Difluoroazetidin-1-yl)-3-fluorobenzaldehyde (CAS 1779130-73-2)
- Carbenoxolone-d4 (CAS 5697-56-3 (Unlabeled))
- 6-Acetylbenzofuran-2-carbonitrile (CAS 2756972-23-1)
- 5-Chloro-2,3-dihydro-2-thioxo-4-pyrimidinecarboxylic Acid (CAS 1023812-22-7)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
Why CATO?
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