Amantadine EP Impurity B CAS 880-52-4
| CAS No. | 880-52-4 |
| Molecular Formula | C12H19NO |
| Molecular Weight | 193.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Amantadine EP Impurity B.
CATO supplies Amantadine EP Impurity B (CAS 880-52-4), a pharmacopoeial impurity reference standard (molecular formula C12H19NO, MW 193.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Amantadine EP Impurity B (C12H19NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Amantadine EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H19NO |
| Molecular Weight | 193.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Amantadine Standards
Recommended Standards
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- Nystatin&Nystatin A1 (CAS CATO-C4X-17161)
- Ethyl 2-cyano-3-oxocyclopentanecarboxylate (CAS 72184-85-1)
- 2-Fluoro-N,N-bis(4-nitrophenyl)aniline (CAS 1864060-72-9)
- 31112-62-6 RHH3W8F1CO Metrizamide Metrizamide [USAN:INN:BAN:JAN] D-Glucose, 2-(3-acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzamido)-2-deoxy- D-Glucose, 2-((3-(acetylamino)-5-(acetylmethylamino)-2,4,6-triiodobenzoyl)amino)-2-deoxy- 2-(3-Acetamido-5-N-methyl-acetamido-2,4,6-triiodobenzamido)-2-deoxy-D-glucose 2-(3-Acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzamido)-2-deoxy-D-glucopyranose 2-(3-Acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzamido)-2-deoxy-D-glucose 2-((3-(Acetylamino)-5-(acetylmethylamino)-2,4,6-triiodobenzoyl)amino)-2-deoxy-D-glucose 3-Acetylamino-5-N-methyl-acetylamino-2,4,6-triiodobenzoyl glucosamine Amipaque CCRIS 7084 EINECS 250-475-5 Metrizamida [INN-Spanish] Metrizamidum [INN-Latin] Telebrix 300 WIN 39103 Metrizamida Metrizamidum UNII-RHH3W8F1CO (CAS 31112-62-6)
- Insulin Degludec Impurity 16 (CAS CATO-C4X-215716)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com