3-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione hydrochloride CAS 88068-72-8
| CAS No. | 88068-72-8 |
| Molecular Formula | C21H24N4O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione hydrochloride (CAS 88068-72-8), molecular formula C21H24N4O3HCl and molecular weight 416.91 g/mol, is a CATO reference standard with documented purity and traceability.
3-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione hydrochloride (C21H24N4O3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H24N4O3 HCl |
| Molecular Weight | 416.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Methoxyphenyl Standards
- 3-(3-Methoxyphenyl)isonicotinic acid (CAS 100004-80-6)
- 3-(2-Methoxyphenyl)isonicotinic acid (CAS 100004-81-7)
- 2-(3-Methoxyphenyl)isonicotinic acid (CAS 100004-95-3)
- 2-(3-Methoxyphenyl)benzo[d]thiazole (CAS 10002-44-5)
- 4-(5-(4-Methoxyphenyl)oxazol-2-yl)aniline (CAS 10004-75-8)
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- Ethyl 2-{[2-(4-methoxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}acetate (CAS 100064-06-0)
- Methyl 5-(2-methoxyphenyl)-1H-pyrrole-2-carboxylate (CAS 1000682-34-7)
Recommended Standards
- Benazolin-ethyl Impurity 15 (CAS 73762-91-1)
- 4-methyl-2-[(4-methylpyrimidin-2-yl)disulfanyl]pyrimidine dihydrochloride (CAS 1461705-83-8)
- Methotrexate-d (CAS 432545-60-3)
- 1-Bromo-3-(1,1-difluoroethyl)-5-fluorobenzene (CAS 627526-99-2)
- 3-Iodo-2-methyl-1H-indole (CAS 2033-44-5)
- 4-[3-(4-Isopropylphenyl)acryloyl]phenyl methanesulfonate (CAS 331460-73-2)
- 3,5-Dimethyl-4-(trifluoromethyl)-1h-pyrazole (CAS 1365265-17-3)
- N-tert-Butyl-N-methylsulfamoyl chloride (CAS 1064037-85-9)
- 6-(3-Phenylpropyl)pyrimidine-2,4(1H,3H)-dione (CAS 13345-13-6)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
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