Lenalidomide Impurity 58 CAS 88071-90-3
| CAS No. | 88071-90-3 |
| Molecular Formula | C9H8BrNO4 |
| Molecular Weight | 274.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Lenalidomide Impurity 58 (CAS 88071-90-3, C9H8BrNO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Lenalidomide Impurity 58 (C9H8BrNO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 274.07 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8BrNO4 |
| Molecular Weight | 274.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Lenalidomide Standards
- Lenalidomide Impurity 16 (CAS 133446-99-8)
- Lenalidomide Impurity 16 (CAS 98475-07-1)
- Lenalidomide Impurity 57 (CAS 90725-68-1)
- Lenalidomide Impurity 59 (CAS 88089-94-5)
- Lenalidomide Impurity 61 (CAS 132874-06-7)
- Lenalidomide Impurity 34 (CAS CATO-C4X-190334)
- Lenalidomide Impurity 17 (CAS 2197421-58-0)
- Lenalidomide Impurity 19 (CAS CATO-C4X-190319)
Recommended Standards
- α-D-Ribose-5-phosphate (CAS 34980-65-9（free base）)
- 7-bromo-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 1021923-54-5)
- Methyl 6-Bromo-2-methyl-3-nitrobenzoate (CAS 731810-03-0)
- 3,4-Dichloro-1-[(2-fluorophenyl)methyl]-2,5-dihydro-1h-pyrrole-2,5-dione (CAS 112749-47-0)
- Clobetasol Propionate EP Impurity G (CAS 25122-41-2)
- Adenine Impurity 2 (CAS CATO-C4X-25912)
- Dobutamine Impurity 39 HCl (CAS CATO-C4X-129839)
- 2-Ethyl-6-isopropylpyridine (CAS 74701-47-6)
- Siponimod Impurity 1 (CAS 877131-21-0)
- cis-3,4-difluoropyrrolidine hydrochloride (CAS 869481-94-7)
- 2-(Chloro(4-chlorophenyl)methyl)benzofuran (CAS 82158-53-0)
- N-(5-Bromo-2-methylpyridin-4-yl)acetamide (CAS 1244949-22-1)
- Methyl 6-mercapto-4-methylnicotinate (CAS 1355180-07-2)
- Acetyl Dipeptide-1 (CAS 196604-48-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com