N-(3-chloro-4-fluorophenyl)-2-(2-(3,4-dimethoxyphenyl)acetyl)hydrazine-1-carbothioamide CAS 882749-28-2
| CAS No. | 882749-28-2 |
| Molecular Formula | C17H17ClFN3O3S |
| Molecular Weight | 397.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(3-chloro-4-fluorophenyl)-2-(2-(3,4-dimethoxyphenyl)acetyl)hydrazine-1-carbothioamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(3-chloro-4-fluorophenyl)-2-(2-(3,4-dimethoxyphenyl)acetyl)hydrazine-1-carbothioamide (CAS 882749-28-2), molecular formula C17H17ClFN3O3S and molecular weight 397.85 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(3-chloro-4-fluorophenyl)-2-(2-(3,4-dimethoxyphenyl)acetyl)hydrazine-1-carbothioamide (C17H17ClFN3O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(3-chloro-4-fluorophenyl)-2-(2-(3,4-dimethoxyphenyl)acetyl)hydrazine-1-carbothioamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H17ClFN3O3S |
| Molecular Weight | 397.85 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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