8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide CAS 883032-94-8
| CAS No. | 883032-94-8 |
| Molecular Formula | C9H6ClF3N4O |
| Molecular Weight | 278.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide (CAS 883032-94-8), molecular formula C9H6ClF3N4O and molecular weight 278.62 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide (C9H6ClF3N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6ClF3N4O |
| Molecular Weight | 278.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- Methyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-7-carboxylate (CAS 1186405-14-0)
- Ethyl 3-chloro-4-cyano-5-(trifluoromethyl)picolinate (CAS 1221792-27-3)
- Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)-pyridine-5-carboxylate (CAS 175277-73-3)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-methyl-1,2,4-oxadiazol-5-amine (CAS 1823183-49-8)
- 5-[[3-Chloro-5-(trifluoromethyl)-2-pyridyl]-methyl]-1,3,4-oxadiazol-2-amine (CAS 1987135-48-7)
- Methyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-cyanoacetate (CAS 658066-43-4)
- 2-Chloro-5-fluorophenyl trifluoromethanesulphonate (CAS 1207669-20-2)
- 2-Chloro-6-fluorophenyl trifluoromethanesulfonate (CAS 1443684-70-5)
Recommended Standards
- Prop-2-ynyl N-[6-chloro-5-(trifluoromethyl)pyridin-3-yl]carbamate (CAS 288246-64-0)
- (8-Aminoquinoline)dichloroCopper (CAS 14751-45-2)
- 3-(6-Chloro-2H-chromen-3-yl)-1,2,4-oxadiazole-5-carboxylic acid (CAS 1269532-45-7)
- 1-[3-Chloro-5-(trifluoromethyl)phenyl]cyclobutanecarboxylic Acid (CAS 1314710-70-7)
- Isochromeno[3',4':4,5]pyrrolo[2,3-f]isoquinolin-8(13H)-one (CAS 5100-91-4)
- 2-Phenyl-4-(phenylsulfonyl)morpholine (CAS 321977-39-3)
- trans-N,N-Diethyl-cyclohexane-1,4-diamine dihydrochloride (CAS 1414958-12-5)
- Cefoperazone Impurity 57 (CAS CATO-C4X-114957)
- 5-Cyclopropoxy-6-(trifluoromethyl)nicotinic acid (CAS 1243348-84-6)
- 3-Chloro-2-mercapto-5-(trifluoromethyl)pyridine 1-oxide (CAS 1823184-14-0)
- N-(2-Bromoacetyl)-1,1-dimethylethyl Ester Glycine (CAS 74010-56-3)
- 5-(4-Bromophenyl)-1-methylimidazole (CAS 136350-71-5)
- Nebivolol Impurity 99 (CAS CATO-C4X-196899)
- [α-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226159)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com