4,7-Dichloro-2-(2-fluorophenyl)quinazoline CAS 885277-55-4
| CAS No. | 885277-55-4 |
| Molecular Formula | C14H7Cl2FN2 |
| Molecular Weight | 293.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4,7-Dichloro-2-(2-fluorophenyl)quinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4,7-Dichloro-2-(2-fluorophenyl)quinazoline (CAS 885277-55-4), molecular formula C14H7Cl2FN2 and molecular weight 293.12 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C14H7Cl2FN2, 4,7-Dichloro-2-(2-fluorophenyl)quinazoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 293.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H7Cl2FN2 |
| Molecular Weight | 293.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 2,4-Dichloro-6-(4-fluorophenyl)quinazoline (CAS 1003042-27-0)
- 4,6-Dichloro-2-(2-fluoro-phenyl)-quinazoline (CAS 885277-47-4)
- 4,6-Dichloro-2-(4-fluoro-phenyl)-quinazoline (CAS 461036-88-4)
- 4,7-Dichloro-2-(4-fluoro-phenyl)-quinazoline (CAS 885277-41-8)
- 2,4-dichloro-8-(trifluoromethoxy)quinazoline (CAS 959237-48-0)
- 6,8-Dichloro-2-phenyl-3,4-dihydro-2h-1-benzopyran-4-one (CAS 100965-49-9)
- Methyl 1-((2,6-dichloro-5-methoxypyrimidin-4-yl)oxy)cyclopropane-1-carboxylate (CAS 1572048-45-3)
- 1,4-Dichloro-5-hydroxyanthracene-9,10-dione (CAS 6770-15-6)
Recommended Standards
- 4-Bromo-N-(4-nitrophenyl)benzenamine (CAS 40932-71-6)
- 3-Bromo-N'-(furan-2-ylmethylene)benzohydrazide (CAS 93418-03-2)
- 4-Chloro-2-(4-chlorophenyl)-6-fluoroquinazoline (CAS 885277-63-4)
- 3-Amino-6-bromo-N-phenylpyrazine-2-carboxamide (CAS 36204-92-9)
- 4-(3-Chloro-4-fluorophenyl)pyrimidin-2-amine (CAS 1249713-59-4)
- 3-[(Aminoiminomethyl)amino]-L-alanine Hydrochloride (CAS 1482-99-1)
- 2,3,4,5,6-PENTAFLUOROCINNAMIC AcidDISCONTINUED (CAS 719-60-8)
- Tert-butyl 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-azaspiro[4.4]Nonane-2-carboxylate (CAS 2304631-27-2)
- Ivabradine impurity 63 (CAS CATO-C4X-111963)
- N-(Furan-2-ylmethyl)-2-((6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-2-yl)thio)acetamide (CAS 887196-62-5)
- 2-(2,5-Dioxo-2,5-dihydro-1h-pyrrol-1-yl)-3-methylbutanoic acid (CAS 148991-43-9)
- Bendamustine Impurity 50 (CAS 5367-53-3)
- 2-(2,4-dichlorophenoxy)-3-nitropyridine (CAS 129199-44-6)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
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