Axitinib Impurity 12 CAS 886230-77-9
| CAS No. | 886230-77-9 |
| Molecular Formula | C19H18IN3O |
| Molecular Weight | 431.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Axitinib Impurity 12 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Axitinib Impurity 12 (CAS 886230-77-9), a certified reference material (molecular formula C19H18IN3O, MW 431.27 g/mol) for analytical method development and quality control.
Structurally, Axitinib Impurity 12 (C19H18IN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 431.27 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Axitinib Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18IN3O |
| Molecular Weight | 431.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Axitinib Standards
- Axitinib Impurity 20 (CAS CATO-C4X-107120)
- Axitinib Impurity 83 (CAS CATO-C4X-107183)
- Axitinib Impurity 24 (CAS CATO-C4X-107124)
- Axitinib impurity 47 (CAS 1639137-80-6)
- Axitinib Impurity 78 (CAS CATO-C4X-107178)
- Axitinib Impurity 35 (CAS 1443118-71-5)
- Axitinib Impurity 33 (CAS CATO-C4X-107133)
- Axitinib Impurity 34 (CAS CATO-C4X-107134)
Recommended Standards
- 4-Iodo-4',4''-dimethoxytriphenylamine (CAS 201802-15-5)
- Boc-(R)-γ-(4-iodo-benzyl)-L-proline (CAS 959573-98-9)
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- 6-Bromo-5-fluoroquinoxaline (CAS 2411639-48-8)
- 4-(2-Aminoethyl)-3-(4-(dimethylamino)phenyl)-5-oxo-2,5-dihydro-1H-pyrazole-1-carboxamide sulfate (CAS 1177351-77-7)
- tert-Butyl (4-(2-hydroxyethoxy)butyl)carbamate (CAS 2361304-25-6)
- 2-Chloro-4-(1h-pyrazol-1-ylmethyl)pyridine (CAS 1250584-89-4)
- Zinc Acetate dihydrate (CAS 5970-45-6)
- 1-Chloro-2-iodo-3-(trifluoromethyl)benzene (CAS 203626-41-9)
- 5-(Cyclopropylamino)-1,3,4-thiadiazole-2-thiol (CAS 852400-37-4)
- 6-Ethynyl-5-azaspiro[2.4]heptane (CAS 2680540-14-9)
- Tirzepatide Impurity 24 X TFA Salt (CAS CATO-C4X-324024)
Why CATO?
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