Axitinib Impurity 20 CAS CATO-C4X-107120
| CAS No. | CATO-C4X-107120 |
| Molecular Formula | C19H18IN3O |
| Molecular Weight | 431.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Axitinib Impurity 20 (C19H18IN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Axitinib Impurity 20 (CAS CATO-C4X-107120) is a certified pharmaceutical impurity reference standard with the molecular formula C19H18IN3O and a molecular weight of 431.27 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Axitinib Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H18IN3O |
| Molecular Weight | 431.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Axitinib Standards
- Axitinib Impurity 12 (CAS 886230-77-9)
- Axitinib Impurity 83 (CAS CATO-C4X-107183)
- Axitinib Impurity 24 (CAS CATO-C4X-107124)
- Axitinib impurity 47 (CAS 1639137-80-6)
- Axitinib Impurity 78 (CAS CATO-C4X-107178)
- Axitinib Impurity 35 (CAS 1443118-71-5)
- Axitinib Impurity 33 (CAS CATO-C4X-107133)
- Axitinib Impurity 34 (CAS CATO-C4X-107134)
Recommended Standards
- Methyl 4-{5-chloro-1-[(3-chlorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-amido}benzoate (CAS 338977-49-4)
- 4-Chloro-N-[2-(6-chloro-4-trifluoromethyl-pyridin-2-ylsulfanyl)-ethyl]-benzenesulfonamide (CAS 1311280-25-7)
- Methyl 2-{5-chloro-1-[(4-chlorophenyl)methyl]-2-oxo-1,2-dihydropyridine-3-amido}benzoate (CAS 338977-29-0)
- Methyl 6-{bis[(tert-butoxy)carbonyl]amino}-5-bromopyridine-3-carboxylate (CAS 1393845-63-0)
- Plerixafor Impurity 7 (12HCl) (CAS CATO-C4X-11337)
- CAS CATO-C3D-1026 (CAS CATO-C3D-1026)
- Riociguat Impurity 25 (CAS CATO-C4X-174925)
- N-Benzyl-2,6-dibromo-3-nitropyridin-4-amine (CAS 1303438-96-1)
- Ethyl 5-amino-2,4-difluorobenzoate (CAS 1159507-72-8)
- (E)-4-Bromo-1-methyl-5-(2-nitrovinyl)-1H-pyrazole (CAS 2629317-98-0)
- 2-Phenyl-N-(thiophen-2-yl)morpholine-4-carboxamide (CAS 1210382-75-4)
- tert-Butyl 2-aminobenzylcarbamate hydrochloride (CAS 1956322-43-2)
- N-(diethylÂaminoÂethylÂ)-4-mesylÂaminoÂbenzÂamide (CAS 101526-83-4)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com