Axitinib Impurity 24 CAS CATO-C4X-107124
| CAS No. | CATO-C4X-107124 |
| Molecular Formula | C24H28N6O2 |
| Molecular Weight | 432.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Axitinib Impurity 24 (CAS CATO-C4X-107124), a pharmacopoeial impurity reference standard (molecular formula C24H28N6O2, MW 432.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Axitinib Impurity 24 (C24H28N6O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 432.52 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C24H28N6O2 |
| Molecular Weight | 432.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Axitinib Standards
- Axitinib Impurity 12 (CAS 886230-77-9)
- Axitinib Impurity 20 (CAS CATO-C4X-107120)
- Axitinib Impurity 78 (CAS CATO-C4X-107178)
- Axitinib Impurity 83 (CAS CATO-C4X-107183)
- Axitinib impurity 47 (CAS 1639137-80-6)
- Axitinib Impurity 33 (CAS CATO-C4X-107133)
- Axitinib Impurity 34 (CAS CATO-C4X-107134)
- Axitinib Impurity 35 (CAS 1443118-71-5)
Recommended Standards
- Myoseverin (CAS 267402-71-1)
- Clobetasol Propionate EP Impurity H (CAS 4351-48-8)
- Ethyl 3-((4-(pyrimidin-2-yl)piperazin-1-yl)sulfonyl)benzo[b]thiophene-2-carboxylate (CAS 941919-12-6)
- Tafluprost 16E-Diene Impurity(Discontinued,See C4X-216310) (CAS CATO-C4X-21631)
- Posaconazole Impurity 77 (CAS 74853-08-0)
- Ibuprofen Impurity 161 (CAS 1928708-57-9)
- Rabeprazole EP Impurity B (CAS 117977-21-6)
- tert-Butyl 5,6-dibromoisoindoline-2-carboxylate (CAS 2720487-05-6)
- 4-(Methylthio)benzo[d]oxazole-2-carbaldehyde (CAS 1803744-83-3)
- 4-(1,3-Dioxaindan-5-ylmethylidene)-2-tert-butyl-1,2,3,4-tetrahydroacridine-9-carboxylic acid (CAS 647036-25-7)
- 1-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]-6-azaspiro[2.5]octane (CAS 1375235-39-4)
- O1-tert-butyl O2-methyl (2R,4S)-4-azidopyrrolidine-1,2-dicarboxylate (CAS 185304-04-5)
- N-(3-(3,4-dichlorophenyl)imidazo[1,2-a]pyridin-8-yl)-3-(trifluoromethyl)benzamide (CAS 338415-25-1)
- D-Ala28-Tirzepatide (CAS CATO-CPTD788906)
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