Isothiazole-4-sulfonyl chloride CAS 88982-55-2
| CAS No. | 88982-55-2 |
| Molecular Formula | C3H2ClNO2S2 |
| Molecular Weight | 183.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Isothiazole-4-sulfonyl chloride (CAS 88982-55-2) is a high-purity analytical reference standard with the molecular formula C3H2ClNO2S2 and a molecular weight of 183.64 g/mol.
Structurally, Isothiazole-4-sulfonyl chloride (C3H2ClNO2S2) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 183.64 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Isothiazole-4-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3H2ClNO2S2 |
| Molecular Weight | 183.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Isothiazole Standards
- Isothiazole-5-sulfonyl chloride (CAS 362658-19-3)
- Ethyl isothiazole-3-carboxylate 1,1-dioxide (CAS 1823946-00-4)
- Isothiazole-4,5-dicarboxylic acid (CAS 66882-70-0)
- Isothiazole-3,4,5-tricarbonitrile (CAS 857958-14-6)
- Ethyl isothiazole-3-carboxylate (CAS 23244-32-8)
- Methyl isothiazole-3-carboxylate (CAS 1001907-72-7)
- 3-Methyl-isothiazole-4-carboxylic acid (CAS 15903-66-9)
- Methyl isothiazole-4-carboxylate (CAS 56133-37-0)
Recommended Standards
- 6-Chloro-N-(cyclopropylmethyl)pyrimidin-4-amine (CAS 928650-17-3)
- 6-Chloro-2-cyclopropyl-5-methylpyrimidin-4-amine (CAS 852061-78-0)
- 3-chloranyl-6-pyrrolidin-1-yl-pyridazine 3-chloro-6-(1-pyrrolidinyl)pyridazine 66346-85-8 A835428 (CAS 66346-85-8)
- 5-Chloro-2-(pyrrolidin-3-yl)pyrimidine (CAS 944903-08-6)
- Methyl 9H-Carbazole-2-carboxylate (CAS 26000-33-9)
- 2-((5-(Trifluoromethyl)pyridin-2-yl)sulfonyl)propanoic acid (CAS 338962-54-2)
- 1,6-Dihydro-5-(2-hydroxyphenyl)-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one 1159977-45-3 5-(2-Hydroxyphenyl)-1,6-dihydro-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one 5-(2-Hydroxyphenyl)-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (CAS 1159977-45-3)
- 2-Hydroxy-5-nitro-m-anisaldehyde (CAS 17028-61-4)
- 3-Mercaptonaphthalen-1-ol (CAS 1824413-19-5)
- Dolutegravir Impurity 13 (CAS 1646862-02-3)
- Thiamine /Vitamin B1 Impurity 51 (CAS CATO-C4X-187351)
- Finerenone Impurity 48 (CAS CATO-C4X-288048)
- 3-(1h-1,2,3-Triazol-1-yl)benzoic acid (CAS 335255-82-8)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com