Amlodipine Impurity 56 CAS 2418591-36-1
| CAS No. | 2418591-36-1 |
| Molecular Formula | C20H23ClN2O6 |
| Molecular Weight | 422.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Amlodipine Impurity 56 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Amlodipine Impurity 56 (CAS 2418591-36-1), a pharmacopoeial impurity reference standard (molecular formula C20H23ClN2O6, MW 422.86 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Amlodipine Impurity 56 (C20H23ClN2O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H23ClN2O6 |
| Molecular Weight | 422.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine Besylate EP Impurity E (CAS 140171-65-9)
- Amlodipine impurity 68 (CAS 88150-30-5)
- Amlodipine impurity 9 (CAS CATO-C4X-10959)
- Amlodipine Impurity 24 (CAS 90445-14-0)
- Amlodipine Impurity 80 (CAS CATO-C4X-109580)
- Amlodipine Impurity 99 (CAS CATO-C4X-109599)
- Amlodipine Impurity 153 (CAS 2923811-73-6)
- Amlodipine Metabolite 4 (CAS 113994-45-9)
Recommended Standards
- Ethyl 3-{[(4-chlorophenyl)carbamoyl]methoxy}pyrido[1,2-a]indole-10-carboxylate (CAS 339107-06-1)
- Dapagliflozin Impurity 171 (CAS CATO-C4X-1138171)
- 6-Amino-4-(4-((2-chlorobenzyl)oxy)-3-methoxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 337499-07-7)
- Dapagliflozin Impurity 20 (CAS 2169998-23-4)
- Mefatinib Impurity 15 (CAS CATO-C4X-299215)
- Parecoxib sodium Impurity 9 (CAS 1373038-56-2)
- Cefdinir Impurity 93 (CAS 206855-75-6)
- 2-Amino-2-(thiophen-2-yl)propanoic acid (CAS 6332-87-2)
- 5-Bromo-2-methoxycyclohepta-2,4,6-trien-1-one (CAS 33816-51-2)
- n-(2,4-Dichlorophenyl)pyrrolidine-2-carboxamide hydrochloride (CAS 1078163-21-9)
- 4-Chloro-2-(difluoromethyl)-3-fluorophenol (CAS 2092380-93-1)
- 5-Methyl-6-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 922186-93-4)
- 4-Bromo-N-((tetrahydrofuran-3-yl)methyl)benzamide (CAS 1184204-55-4)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com