1-(5-Chloro-2-methylphenyl)-N-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAS 890937-57-2
| CAS No. | 890937-57-2 |
| Molecular Formula | C24H18ClN5O |
| Molecular Weight | 427.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(5-Chloro-2-methylphenyl)-N-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (C24H18ClN5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(5-Chloro-2-methylphenyl)-N-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 890937-57-2), molecular formula C24H18ClN5O and molecular weight 427.89 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(5-Chloro-2-methylphenyl)-N-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H18ClN5O |
| Molecular Weight | 427.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- ErlotiniB impurity 37 (CAS CATO-C4X-106937)
- 3-(4-Chlorophenyl)-5-(methylsulfanyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-carboxamide (CAS 477858-03-0)
- (1R,2R,3R,4S,5R,6S,7S,8S)-4-bromocubane-1-carboxylic acid (CAS 37794-29-9)
- 2-Ethynyl-2-methyl-6-phenyl-5-(prop-1-en-2-yl)tetrahydro-2H-pyran (CAS 320784-75-6)
- 2-(Pyridin-3-ylamino)naphtho[2,3-d]thiazole-4,9-dione (CAS 1313739-00-2)
- Rhenium pentacarbonyl(I) bromide (CAS 14220-21-4)
- Nitrendipine (CAS 39562-70-4)
- (E)-1,2,3-Tribromo-But-2-Ene (CAS 40049-80-7)
- 1-[2-(Trifluoromethyl)phenyl]cyclobutanamine (CAS 1314785-94-8)
- 2-(2-Hydroxyethoxy)ethyl acetate (CAS 2093-20-1)
- 5-(4-Bromo-2-methylphenyl)-1,3-oxazole (CAS 501944-47-4)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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