3-(4-Chlorophenyl)-5-(methylsulfanyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-carboxamide CAS 477858-03-0
| CAS No. | 477858-03-0 |
| Molecular Formula | C19H13ClF3NOS2 |
| Molecular Weight | 427.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Chlorophenyl)-5-(methylsulfanyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-carboxamide.
3-(4-Chlorophenyl)-5-(methylsulfanyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-carboxamide (CAS 477858-03-0), molecular formula C19H13ClF3NOS2 and molecular weight 427.89 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 3-(4-Chlorophenyl)-5-(methylsulfanyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 427.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-Chlorophenyl)-5-(methylsulfanyl)-N-[4-(trifluoromethyl)phenyl]thiophene-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H13ClF3NOS2 |
| Molecular Weight | 427.89 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 5-(4-Chlorophenyl)-3-hydroxy-4-(4-methoxybenzoyl)-1-((tetrahydrofuran-2-yl)methyl)-1H-pyrrol-2(5H)-one (CAS 496798-24-4)
- Ethyl 2-(4-(3-chlorophenyl)piperazin-1-yl)-5-(4-fluorophenyl)-1H-pyrrole-3-carboxylate (CAS 338406-24-9)
- 1-(4-Chlorophenyl)-5-[(2E)-3-(dimethylamino)prop-2-enoyl]-3-[(4-fluorophenyl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 338770-05-1)
- 2-(4-Chlorophenyl)-2-oxoethyl 1-butyl-6-oxo-2-phenylpiperidine-3-carboxylate (CAS 477890-10-1)
- Methyl 1-{5-[(4-chlorophenyl)methyl]-4,6-dimethylpyrimidin-2-yl}-5-pentyl-1H-1,2,3-triazole-4-carboxylate (CAS 866040-44-0)
- 5-[(4-Chlorophenyl)sulfanyl]-2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-(4-methoxyphenyl)-1,3-thiazole (CAS 956573-31-2)
- N-(2-((4-(3-Chlorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(thiophen-2-yl)acetamide (CAS 897613-19-3)
- 4-{[(4-chlorophenyl)sulfanyl]methyl}-6-[(2,4-dichlorophenyl)sulfanyl]-2-methylpyrimidine (CAS 339278-79-4)
Recommended Standards
- 1-(Adamantane-1-carbonyl)-4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazine (CAS 339098-58-7)
- 2-Amino-1-(3-((4-chlorophenyl)amino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethanone (CAS 1261114-01-5)
- 1-(5-Chloro-2-methylphenyl)-N-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 890937-57-2)
- 5-(2-Chlorobenzyl)-7-(3,4-dimethoxyphenyl)-2-methylthiazolo[4,5-d]pyridazin-4(5H)-one (CAS 941949-93-5)
- (3R,3'R)-BABIBOP (CAS 2214207-73-3)
- 3-(pyrimidin-2-yloxy)aniline (CAS 176032-34-1)
- 4-(2-(Aminomethyl)cyclopropyl)benzonitrile (CAS 1343762-03-7)
- N-(9H-Fluoren-2-yl)formamide (CAS 6957-71-7)
- 2,3-Dichloro-5-(difluoromethyl)pyridine-6-carboxylic acid (CAS 1806803-16-6)
- 4-Bromo-1-(3-fluorobenzyl)pyridin-2(1h)-one (CAS 1877278-49-3)
- 2,6-Difluoro-3,4,5-trihydroxybenzoic acid (CAS 198832-21-2)
- 5-Chloro-3-iodo-4,6-dimethylpyridin-2-amine (CAS 1823869-84-6)
- (2-Cyclopropyl-5-fluoropyridin-4-yl)boronic acid (CAS 2225174-24-1)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com