2-(2-Chloro-6-nitrophenyl)acetonitrile CAS 89277-98-5
| CAS No. | 89277-98-5 |
| Molecular Formula | C8H5ClN2O2 |
| Molecular Weight | 196.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(2-Chloro-6-nitrophenyl)acetonitrile (CAS 89277-98-5) is a high-purity analytical reference standard with the molecular formula C8H5ClN2O2 and a molecular weight of 196.59 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-(2-Chloro-6-nitrophenyl)acetonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 196.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-(2-Chloro-6-nitrophenyl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2O2 |
| Molecular Weight | 196.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-2-methyl-4-nitrobenzonitrile (CAS 101495-54-9)
- 7-Chloro-2H-indazole-5-carboxylic acid (CAS 1031417-54-5)
- 3-Chloro-1H-indazole-5-carboxylic acid (CAS 1031417-73-8)
- 5-Chloro-1H-indazole-3-carboxylic acid (CAS 1077-95-8)
- 5-Chloro-2-methyl-3-nitro-benzonitrile (CAS 1082040-48-9)
- 2-(2-Chloro-3-nitrophenyl)acetonitrile (CAS 108772-95-8)
- 6-Chloro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS 1167056-92-9)
- Methyl 3-chloro-2-cyano-pyridine-4-carboxylate (CAS 1168102-35-9)
Recommended Standards
- 2-(2-Chloro-5-nitrophenyl)acetonitrile (CAS 52427-02-8)
- 2-(3-Chloro-2-nitrophenyl)acetonitrile (CAS 77158-79-3)
- 2-(2-Chloro-4-nitrophenyl)acetonitrile (CAS 89277-99-6)
- 2-(4-Chloro-2-nitrophenyl)acetonitrile (CAS 87081-90-1)
- 2-Amino-2-(6-chloro-1H-benzo[d]imidazol-2-yl)ethan-1-ol (CAS 719999-62-9)
- (5-(1,3,4-Thiadiazol-2-yl)pyridin-3-yl)methanol (CAS 1346687-63-5)
- 1-(chloromethyl)-4-(methoxymethyl)benzene (CAS 52889-83-5)
- 3-((2,4-Dichlorophenoxy)methyl)-5-(3-((4-fluorobenzyl)oxy)thiophen-2-yl)-4H-1,2,4-triazole (CAS 400081-69-8)
- 2-[(4-chlorophenyl)methanesulfonyl]acetonitrile (CAS 175137-57-2)
- Methyl 5-(Chlorosulfonyl)-1H-pyrazole-4-carboxylate (CAS 1532000-54-6)
- 2-((3,5-bis(Trifluoromethyl)phenyl)amino)-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 1797782-24-1)
- 2,2,2-trifluoroethyl N-(quinolin-3-yl)carbamate (CAS 1455104-41-2)
- Tofacitinib Impurity 142 (CAS 1431697-80-1)
- Semaglutide (CAS CATO-C4X-2226105)
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