Tolvaptan Impurity 48 CAS 897-82-5
| CAS No. | 897-82-5 |
| Molecular Formula | C14H12ClNO4S |
| Molecular Weight | 325.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tolvaptan Impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Tolvaptan Impurity 48 (CAS 897-82-5) is a high-purity analytical reference standard with the molecular formula C14H12ClNO4S and a molecular weight of 325.77 g/mol.
Tolvaptan Impurity 48 (C14H12ClNO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H12ClNO4S |
| Molecular Weight | 325.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Tolvaptan Standards
- Tolvaptan Impurity 11 (CAS 137977-97-0)
- Tolvaptan Impurity 8 (CAS 1432725-24-0)
- Tolvaptan Impurity 92 (CAS 1580889-22-0)
- Tolvaptan impurity 114 (CAS CATO-C4X-1955114)
- Tolvaptan Impurity 121 (CAS CATO-C4X-1955121)
- Tolvaptan Impurity 31 (CAS 1580889-21-9)
- Tolvaptan Impurity 122 (CAS CATO-C4X-1955122)
- Tolvaptan Impurity 128 (CAS CATO-C4X-1955128)
Recommended Standards
- Sulpiride Impurity 25 (CAS 313259-41-5)
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