Toremifene impurity 01 CAS 89778-26-7
| CAS No. | 89778-26-7 |
| Molecular Formula | C26H28ClNO |
| Molecular Weight | 405.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Toremifene impurity 01.
As a process- or degradation-related impurity, Toremifene impurity 01 (CAS 89778-26-7, C26H28ClNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Toremifene impurity 01 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 405.96 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Toremifene impurity 01 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H28ClNO |
| Molecular Weight | 405.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Toremifene Standards
- Toremifene impurity 8 (CAS 89778-29-0)
- Toremifene impurity 6 (CAS CATO-C4X-13976)
- Toremifene N-Oxide (CAS 163130-29-8)
- Toremifene Impurity 4 (CAS 97151-04-7)
- Toremifene Impurity 3 (CAS 1798421-30-3)
- Toremifene Impurity 74 (CAS CATO-C4X-13974)
- Toremifene impurity 7 (CAS 604010-60-8)
- Toremifene (CAS 89778-27-8)
Recommended Standards
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- Imatinib (CAS 152459-95-5)
- 1-Ethyl-4-iodo-1h-pyrazole-5-carbonitrile (CAS 1354704-03-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com