Darunavir impurity 31 CAS 1291087-81-4
| CAS No. | 1291087-81-4 |
| Molecular Formula | C34H45N3O11S |
| Molecular Weight | 703.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Darunavir impurity 31 (CAS 1291087-81-4), a pharmacopoeial impurity reference standard (molecular formula C34H45N3O11S, MW 703.80 g/mol) used for the identification and quantification of trace impurities in APIs.
Darunavir impurity 31 (C34H45N3O11S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Darunavir impurity 31 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C34H45N3O11S |
| Molecular Weight | 703.80 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Darunavir Standards
- Darunavir Impurity 24 (CAS 1971057-59-6)
- Darunavir-N-glucuronide, 96% (CAS 1159613-25-8)
- Darunavir O-β-D-glucuronide, 96% (CAS 1159613-27-0)
- Darunavir Impurity 20 (CAS 2307745-62-4)
- Darunavir impurity 30 (CAS CATO-C4X-160630)
- Darunavir Impurity 36 (CAS CATO-C4X-160636)
- Darunavir-d9 (CAS 1133378-37-6)
- D-Darunavir (CAS 1399859-60-9)
Recommended Standards
- Methyl (E)-5-(2-(4-((4-chlorophenyl)thio)-3-(2,6-dichlorophenyl)isoxazolo[4,5-c]pyridin-7-yl)vinyl)-3-(2,6-dichlorophenyl)isoxazole-4-carboxylate (CAS 338773-22-1)
- Suc-Ala-Leu-Pro-Phe-AMC (CAS 142997-31-7)
- Brecanavir, >98% (HPLC) (CAS 313682-08-5)
- Desbenzoyl Docetaxel (CAS 160972-48-5)
- Gliclazide Impurity 14 (CAS 98431-87-9)
- Avatrombopag Impurity 72 (CAS CATO-C4X-223472)
- Rasagiline Impurity 14 HCl (CAS 200628-33-7)
- 3-(Thiophen-3-yl)isoxazole (CAS 103092-70-2)
- GSK 525762A (CAS 1260907-17-2)
- 5-Fluorobenzo[d][1,2,3]triazin-4(3H)-one (CAS 898554-22-8)
- 1292766-21-2 C26H28O7 Pierreione B W2824 (CAS 1292766-21-2)
- Methyl 5-methoxy-3-propoxythiophene-2-carboxylate (CAS 1708079-42-8)
- 1-Isopropyl-4-piperidone (CAS 5355-68-0)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com