(3-(1,3-Dioxolan-2-yl)phenyl)(2-chloro-4-fluorophenyl)methanone CAS 898759-40-5

Purity 97%+In StockPharmaceutical Standards
CAS No.898759-40-5
Molecular FormulaC16H12ClFO3
Molecular Weight306.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3-(1,3-Dioxolan-2-yl)phenyl)(2-chloro-4-fluorophenyl)methanone CAS 898759-40-5 chemical structure

Description

The occurrence of (3-(1,3-Dioxolan-2-yl)phenyl)(2-chloro-4-fluorophenyl)methanone is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(3-(1,3-Dioxolan-2-yl)phenyl)(2-chloro-4-fluorophenyl)methanone (CAS 898759-40-5), molecular formula C16H12ClFO3 and molecular weight 306.72 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (3-(1,3-Dioxolan-2-yl)phenyl)(2-chloro-4-fluorophenyl)methanone (C16H12ClFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), (3-(1,3-Dioxolan-2-yl)phenyl)(2-chloro-4-fluorophenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H12ClFO3
Molecular Weight306.72 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl-containing

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