5-(1,3-Dioxolan-2-yl)-2-(3-nitrobenzoyl)thiophene CAS 898778-31-9
| CAS No. | 898778-31-9 |
| Molecular Formula | C14H11NO5S |
| Molecular Weight | 305.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-(1,3-Dioxolan-2-yl)-2-(3-nitrobenzoyl)thiophene (CAS 898778-31-9), a certified reference material (molecular formula C14H11NO5S, MW 305.31 g/mol) for analytical method development and quality control.
The molecular framework of 5-(1,3-Dioxolan-2-yl)-2-(3-nitrobenzoyl)thiophene (C14H11NO5S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11NO5S |
| Molecular Weight | 305.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dioxolan Standards
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- 2-(4-((1,3-Dioxolan-2-yl)methoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 850411-10-8)
- 5-(1,3-Dioxolan-2-yl)-2-(4-ethoxybenzoyl)thiophene (CAS 898778-61-5)
- (3-(1,3-Dioxolan-2-yl)phenyl)(2-chloro-4-fluorophenyl)methanone (CAS 898759-40-5)
- (3-(1,3-Dioxolan-2-yl)phenyl)(4-chloro-3-fluorophenyl)methanone (CAS 898779-51-6)
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Recommended Standards
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- 6-(4-Fluorobenzyl)-3-(morpholinoamino)-1,2,4-triazin-5(4H)-one (CAS 881438-04-6)
- Ethyl (4-Trifluoromethylbenzoyl)acetate (CAS 106263-53-0)
- 4-Methyl-2-(o-tolylamino)pyrimidine-5-carboxylic acid (CAS 941266-33-7)
- (4,5-Dibromothiophen-3-yl)methanol (CAS 73919-89-8)
- 4-Bromo-2-(bromomethyl)benzo[b]thiophene (CAS 1312118-04-9)
- 2-ethenylfuran-3-carboxylic acid (CAS 1467773-65-4)
- 4-(4-(m-Tolyl)-1H-pyrazol-3-yl)-4H-1,2,4-triazole (CAS 62538-00-5)
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