(4-(1,3-Dioxolan-2-yl)phenyl)(3,4,5-trifluorophenyl)methanone CAS 898760-82-2
| CAS No. | 898760-82-2 |
| Molecular Formula | C16H11F3O3 |
| Molecular Weight | 308.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(4-(1,3-Dioxolan-2-yl)phenyl)(3,4,5-trifluorophenyl)methanone (CAS 898760-82-2) is a high-purity analytical reference standard with the molecular formula C16H11F3O3 and a molecular weight of 308.25 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, (4-(1,3-Dioxolan-2-yl)phenyl)(3,4,5-trifluorophenyl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 308.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H11F3O3 |
| Molecular Weight | 308.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Dioxolan Standards
- 3-(1,3-Dioxolan-2-yl)-3,4,5-trifluorobenzophenone (CAS 898759-70-1)
- 4-(2-Methyl-1,3-dioxolan-2-yl)pyridine (CAS 60553-33-5)
- (3-(1,3-Dioxolan-2-yl)phenyl)(2-chloro-4-fluorophenyl)methanone (CAS 898759-40-5)
- (3-(1,3-Dioxolan-2-yl)phenyl)(4-chloro-3-fluorophenyl)methanone (CAS 898779-51-6)
- (4-(1,3-Dioxolan-2-yl)phenyl)(3-chloro-4-fluorophenyl)methanone (CAS 898760-40-2)
- (4-(1,3-Dioxolan-2-yl)phenyl)(4-chloro-3-fluorophenyl)methanone (CAS 898760-37-7)
- 2-(3-((1,3-Dioxolan-2-yl)methoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 850411-08-4)
- 2-(4-((1,3-Dioxolan-2-yl)methoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 850411-10-8)
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