3-hydroxy-3-(trifluoromethyl)piperazin-2-one CAS 89972-18-9
| CAS No. | 89972-18-9 |
| Molecular Formula | C5H7F3N2O2 |
| Molecular Weight | 184.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-hydroxy-3-(trifluoromethyl)piperazin-2-one.
3-hydroxy-3-(trifluoromethyl)piperazin-2-one (CAS 89972-18-9) is a high-purity analytical reference standard with the molecular formula C5H7F3N2O2 and a molecular weight of 184.12 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 3-hydroxy-3-(trifluoromethyl)piperazin-2-one is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-hydroxy-3-(trifluoromethyl)piperazin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H7F3N2O2 |
| Molecular Weight | 184.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related hydroxy Standards
- 3-Hydroxy-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1163729-49-4)
- 6-Hydroxy-4-nitropicolinic acid (CAS 1393572-16-1)
- 6-Hydroxy-5-nitropicolinic acid (CAS 1595036-59-1)
- cis-3-hydroxy-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1690177-86-6)
- (R)-4-hydroxy-4-(trifluoromethyl)tetrahydro-2H-pyran-2-one (CAS 956398-59-7)
- (s)-4-Hydroxy-4-(trifluoromethyl)tetrahydro-2h-pyran-2-one (CAS 956398-58-6)
- 3-Hydroxy-3-(trifluoromethyl)tetrahydro-4H-pyran-4-one (CAS 693245-82-8)
- 4-Hydroxy-4-(trifluoromethyl)tetrahydro-2H-pyran-2-one (CAS 83191-83-7)
Recommended Standards
- 3-Fluoro-5-formyl-4-hydroxybenzoic acid (CAS 2166833-12-9)
- 4-(trifluoromethyl)-1H-imidazole-2-carboxylic acid (CAS 915230-46-5)
- 3-Fluoro-4-nitrobenzamide (CAS 3556-52-3)
- 4-Fluoro-3-nitrobenzamide (CAS 349-02-0)
- 1-Butanamine, N-(phenylmethoxy)- (CAS 216237-14-8)
- (3S,5S)-5-methylpyrrolidine-3-carboxylic acid (CAS 1932634-30-4)
- 5-(Bromomethyl)-3-methyl-1-phenyl-1H-pyrazole (CAS 1020724-91-7)
- 1-BENZYLPYRROLIDINE-2-CARBOXAMIDE (CAS 60169-70-2)
- 1,1'-(Oxybis(4,1-phenylene))bis(1H-imidazole) (CAS 13120-43-9)
- (S)-1-(2-(Difluoromethoxy)-4-fluorophenyl)ethan-1-amine (CAS 1344957-66-9)
- (R)-2-((tert-Butoxycarbonyl)amino)-3-(3-hydroxyphenyl)propanoic acid (CAS 90819-32-2)
- 1-(2,6-Dimethylphenyl)-3-phenylpropan-1-one (CAS 898764-30-2)
- N-Nitroso Levetiracetam Impurity 39 (CAS CATO-C4X-106739)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com