Rebamipide Impurity 2 CAS 90098-06-9
| CAS No. | 90098-06-9 |
| Molecular Formula | C19H15ClN2O4 |
| Molecular Weight | 370.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rebamipide Impurity 2 (CAS 90098-06-9) is a certified pharmaceutical impurity reference standard with the molecular formula C19H15ClN2O4 and a molecular weight of 370.79 g/mol.
Structurally, Rebamipide Impurity 2 (C19H15ClN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 370.79 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rebamipide Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H15ClN2O4 |
| Molecular Weight | 370.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Rebamipide Standards
- Rebamipide (CAS 90098-04-7)
- Rebamipide Impurity 3 (CAS 90098-05-8)
- Rebamipide Impurity 30 (CAS CATO-C4X-152330)
- Rebamipide impurity 01 (CAS 4900-38-3)
- Rebamipide-d4 (CAS 1219409-06-9)
- Rebamipide Impurity 60 (CAS 135252-30-1)
- Rebamipide Impurity 6 (CAS 90098-38-7)
- Rebamipide Impurity 56 (CAS CATO-C4X-152356)
Recommended Standards
- N4, N5-Dinitroso Clozapine EP Impurity C (CAS CATO-C4X-134024)
- N-[(4-Chlorophenyl)methoxy]-N-{[(4E)-5-oxo-2-phenyl-4,5-dihydro-1,3-oxazol-4-ylidene]methyl}acetamide (CAS 339028-71-6)
- 4-(4-Chloro-2-fluorobenzoyl)-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326815-25-1)
- N-(benzo[d][1,3]dioxol-5-ylmethyl)-3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamide (CAS 312319-23-6)
- Olopatadine Impurity 49 (CAS CATO-C4X-171849)
- Levothyroxine Impurity 24 (CAS CATO-C4X-167824)
- Cefuroxime Impurity 98 (CAS CATO-C4X-124598)
- N-(6-Amino-4-methoxy-benzothiazol-2-yl)-acetamide (CAS 314033-54-0)
- N,N-Dimethyl-2-((tetrahydrothiophen-3-yl)oxy)isonicotinamide (CAS 2034238-80-5)
- Indacaterol Impurity 93 (CAS 1640894-03-6)
- 2-Chloro-3-phenylsulfonamidopyridine-5-boronic acid pinacol ester, 97% (CAS 1083326-55-9)
- 2-(Dimethylphosphoryl)benzaldehyde (CAS 2287310-50-1)
- [(2-chlorophenyl)methyl](methoxy)amine hydrochloride (CAS 1803609-35-9)
- Peptide Impurity 34 (CAS 21282-09-7)
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