Rebamipide Impurity 6 CAS 90098-38-7
| CAS No. | 90098-38-7 |
| Molecular Formula | C20H17ClN2O4 |
| Molecular Weight | 384.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Rebamipide Impurity 6 (CAS 90098-38-7), a pharmacopoeial impurity reference standard (molecular formula C20H17ClN2O4, MW 384.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Rebamipide Impurity 6 (C20H17ClN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17ClN2O4 |
| Molecular Weight | 384.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Rebamipide Standards
- Rebamipide impurity 18 (CAS CATO-C4X-152318)
- Rebamipide-d4 (CAS 1219409-06-9)
- Rebamipide impurity 01 (CAS 4900-38-3)
- Rebamipide impurity 21 (CAS 452322-61-1)
- Rebamipide (CAS 90098-04-7)
- Rebamipide Impurity 2 (CAS 90098-06-9)
- Rebamipide Impurity 3 (CAS 90098-05-8)
- Rebamipide Impurity 30 (CAS CATO-C4X-152330)
Recommended Standards
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