5-Chloro-1H-pyrrolo[2,3-b]pyridine-2,3-dione CAS 905092-64-0
| CAS No. | 905092-64-0 |
| Molecular Formula | C7H3ClN2O2 |
| Molecular Weight | 182.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Chloro-1H-pyrrolo[2,3-b]pyridine-2,3-dione (CAS 905092-64-0), a certified reference material (molecular formula C7H3ClN2O2, MW 182.56 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-1H-pyrrolo[2,3-b]pyridine-2,3-dione (C7H3ClN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 5-Chloro-1H-pyrrolo[2,3-b]pyridine-2,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClN2O2 |
| Molecular Weight | 182.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 6-Chloro-5-cyanopicolinic acid (CAS 53234-56-3)
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- Bumetanide Impurity 80 (CAS CATO-C4X-198680)
- (5-Bromo-6-(4-methyl-1H-pyrazol-1-yl)pyridin-3-yl)boronic acid (CAS 2225155-79-1)
- 2-Chloro-3-fluoroquinoxaline (CAS 303762-31-4)
- (S)-1-amino-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol dihydrochloride (CAS 2387569-03-9)
- (3-Methoxyphenyl)(3-methylpyridin-2-yl)methanone (CAS 1187164-04-0)
- Pioglitazone impurity 49 (CAS CATO-C4X-138349)
- Tirzepatide Impurity 1 (CAS 2460751-66-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com