Bumetanide Impurity 80 CAS CATO-C4X-198680
| CAS No. | CATO-C4X-198680 |
| Molecular Formula | C7H5ClN2O6S |
| Molecular Weight | 280.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bumetanide Impurity 80 (CAS CATO-C4X-198680) is a certified pharmaceutical impurity reference standard with the molecular formula C7H5ClN2O6S and a molecular weight of 280.64 g/mol.
Based on its molecular formula C7H5ClN2O6S, Bumetanide Impurity 80 contains a carbohydrate-derived structure, an amide group, a sulfone group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 280.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2O6S |
| Molecular Weight | 280.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bumetanide Standards
- Bumetanide Impurity 45 (CAS 61658-42-2)
- Bumetanide Impurity 133 (CAS CATO-C4X-1986133)
- Bumetanide Impurity 48 (CAS CATO-C4X-198648)
- Bumetanide Impurity 5 (CAS 22892-96-2)
- Bumetanide Impurity 73 (CAS CATO-C4X-198673)
- Bumetanide Impurity 7 (CAS 130262-91-8)
- Bumetanide Impurity 40 (CAS 688047-82-7)
- Bumetanide Impurity 78 (CAS CATO-C4X-198678)
Recommended Standards
- 2-Chloro-N-(4,5,6-trifluoro-1,3-benzothiazol-2-yl)acetamide (CAS 379255-48-8)
- 3-Chloro-6-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid (CAS 923849-73-4)
- 5-Chloro-3-trifluoromethylbenzo[b]thiophene-2-carboxylic acid (CAS 752135-60-7)
- Ethyl 4-chloro-6-nitroquinoline-3-carboxylate (CAS 103514-54-1)
- Fluconazole EP Impurity H (CAS 150194-52-8)
- Ketotifen Impurity 30 (CAS CATO-C4X-204630)
- Ibrutinib Impurity 164 (CAS CATO-C4X-1064164)
- N-(2,4,5-Trimethoxybenzyl)-3-pentanamine hydrobromide (CAS 1609402-77-8)
- Ethyl 6-amino-2-chloro-5-nitropyrimidine-4-carboxylate (CAS 15949-13-0)
- 2,3-Dibromo-6-fluorobenzoyl chloride (CAS 1804417-33-1)
- N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium chloride xcalcium salt (CAS 15557-11-6)
- 3-(4-piperidyl)propanal (CAS 15848-31-4)
- 4-Phenyl-2-(piperidin-4-yl)thiazole (CAS 887624-98-8)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
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