Atorvastatin Calcium EP Impurity Q CAS 906552-18-9
| CAS No. | 906552-18-9 |
| Molecular Formula | C33H35FN2O6 |
| Molecular Weight | 574.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Atorvastatin Calcium EP Impurity Q (CAS 906552-18-9, C33H35FN2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Atorvastatin Calcium EP Impurity Q (C33H35FN2O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Atorvastatin Calcium EP Impurity Q under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C33H35FN2O6 |
| Molecular Weight | 574.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Atorvastatin Standards
- Atorvastatin Impurity 16 (CAS CATO-C4X-113216)
- Atorvastatin Calcium EP Impurity M (CAS 345891-62-5)
- Atorvastatin EP Impurity C Sodium Salt (CAS 1807481-00-0)
- Atorvastatin EP Impurity C (CAS 693794-20-6)
- Atorvastatin Lactone Diepoxide (CAS 1046118-40-4)
- Atorvastatin Impurity 105 (CAS CATO-C4X-1132105)
- 3-Oxo Atorvastatin Methyl Ester (CAS 2206606-73-5)
- Atorvastatin Lactam Phenanthrene Methyl Ester(Mixture of Diastereomers) (CAS 906552-20-3)
Recommended Standards
- o-Hydroxy Atorvastatin-d (CAS 214217-88-6)
- Tos-Gly-Pro-Lys-pNA (CAS 73392-19-5)
- Cyclo(-Arg-Gly-Asp-D-Phe-Val) (CAS 137813-35-5)
- 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-oic acid (CAS 1639205-66-5)
- Acotiamide Impurity 22 (CAS 877997-98-3)
- Nemonoxacin Impurity 32 (CAS CATO-C4X-312832)
- Fluticasone Furoate Impurity 4 (CAS CATO-C4X-32544)
- 2-(4-Oxopiperidin-1-yl)acetic acid (CAS 218772-96-4)
- 2-(3-Ethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3(2H)-one (CAS 1189423-81-1)
- Bis(4-fluorophenyl)-1,2-oxazol-5-amine (CAS 1096934-22-3)
- 3-Bromo-5-(2-ethoxycarbonylbenzoyl)pyridine (CAS 898771-80-7)
- N-Nitroso Tamsulosin (CAS CATO-C4X-118769)
- 5-Methoxy-1H-benzo[d]imidazol-1-ol (CAS 134353-33-6)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com