7-amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-5-ol Hydrochloride CAS 914205-08-6
| CAS No. | 914205-08-6 |
| Molecular Formula | C6H4F3N5O |
| Molecular Weight | 219.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 7-amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-5-ol Hydrochloride (CAS 914205-08-6), a certified reference material (molecular formula C6H4F3N5O, MW 219.12 g/mol) for analytical method development and quality control.
The molecular framework of 7-amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-5-ol Hydrochloride (C6H4F3N5O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 7-amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-5-ol Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4F3N5O |
| Molecular Weight | 219.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related amino Standards
- 2-Amino-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (CAS 326906-13-2)
- 2-Amino-5-(perfluoroethyl)-1,3,4-thiadiazole (CAS 51314-64-8)
- 2-Amino-5-bromo-4-cyclopropylthiazole (CAS 869854-12-6)
- (4-Amino-2-(difluoromethyl)-5-nitropyridin-3-yl)methanol (CAS 1805220-79-4)
- (4-Amino-3-(difluoromethyl)-5-nitropyridin-2-yl)methanol (CAS 1805354-72-6)
- (4-Amino-6-(difluoromethyl)-5-nitropyridin-2-yl)methanol (CAS 1805367-99-0)
- (2-Amino-6-(difluoromethyl)-5-nitropyridin-3-yl)methanol (CAS 1805992-16-8)
- (6-Amino-5-(difluoromethyl)-4-nitropyridin-3-yl)methanol (CAS 1806890-48-1)
Recommended Standards
- 7-(Trifluoromethyl)imidazo[1,2-a]pyrimidine-2,5(1H,3H)-dione (CAS 294878-92-5)
- 7-bromo-6-methyl-imidazo[1,2-a]pyridine (CAS 2089158-09-6)
- 7-(Bromomethyl)-6-oxaspiro[3.5]nonane (CAS 2090711-56-9)
- 7-bromo-8-methyl-imidazo[1,2-a]pyridine (CAS 2056080-87-4)
- 3-(Trifluoromethyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-9-amine (CAS 1707391-57-8)
- Ethyl 3-(4-fluorophenyl)-2,2-dimethylpropanoate (CAS 676621-95-7)
- 4-Bromo-2,5-difluoro-N-methylbenzamide (CAS 1621165-12-5)
- 3-vinyl-3,4-dihydro-1,2-dithiine (CAS 62488-53-3)
- 5-Fluoro-4-hydroxynicotinaldehyde (CAS 1289068-72-9)
- Fludarabine Phosphate EP Impurity E (CAS 21679-14-1)
- 1-Amino-3-(3-methyl-1h-pyrazol-1-yl)cyclopentane-1-carboxamide (CAS 1516303-62-0)
- 1-(Benzo[d][1,3]dioxol-5-yl)-2-((4-methyl-6-(trifluoromethyl)pyrimidin-2-yl)thio)ethan-1-one (CAS 940984-29-2)
- Hyoscyamine Impurity 10 (CAS CATO-C4X-343710)
- Pancreatic Polypeptide (bovine) (CAS 179986-89-1)
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