Piperaquine tetraPhosphate tetrahydrate CAS 915967-82-7
| CAS No. | 915967-82-7 |
| Molecular Formula | C29H32Cl2N6 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Piperaquine tetraPhosphate tetrahydrate (C29H32Cl2N6H3O4PH2O) is characterized by a steroid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Piperaquine tetraPhosphate tetrahydrate (CAS 915967-82-7) is a high-purity analytical reference standard with the molecular formula C29H32Cl2N6H3O4PH2O and a molecular weight of 651.53 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H32Cl2N6 4*H3O4P 4*H2O |
| Molecular Weight | 651.53 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Piperaquine Standards
- Piperaquine Impurity 9 (CAS 1233345-93-1)
- Piperaquine D6 (CAS 1261394-71-1)
- Piperaquine Impurity N1 (CAS 4038-99-7)
- Piperaquine Impurity N4 (CAS 4039-00-3)
- Piperaquine Base (CAS 4085-31-8)
- Piperaquine Phosphate (CAS 85547-56-4)
- Piperaquine Tetraphosphate (CAS 911061-10-4)
- Piperaquine Impurity 8 (CAS 918879-09-1)
Recommended Standards
- 4-(2-Fluorophenyl)piperidine (CAS 180161-17-5)
- N-Succinimidyl 7-(Diethylamino)coumarin-3-carboxylate (CAS 139346-57-9)
- Octadecyl(triphenyl)phosphonium bromide (CAS 59514-47-5)
- 898768-63-3 Ethyl 4-[3-(4-methylphenyl)propanoyl]benzoate DTXSID70644117 (CAS 898768-63-3)
- 2-Phenyl-1h-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1261804-09-4)
- N,4-Dihydroxy-3,5-dimethylbenzimidamide (CAS 162854-15-1)
- PF 04859989 (CAS 34783-48-7)
- 2-(3-Methoxyphenyl)benzo[d]thiazole (CAS 10002-44-5)
- 2-((3,3-Dimethylcyclohexyl)amino)-N,N-dimethylacetamide (CAS 1343004-07-8)
- Semaglutide impurity 235 (CAS CATO-C4X-2226235)
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