Piperaquine Impurity N4 CAS 4039-00-3
| CAS No. | 4039-00-3 |
| Molecular Formula | C20H28ClN5 |
| Molecular Weight | 373.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Piperaquine Impurity N4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Piperaquine Impurity N4 (CAS 4039-00-3), a pharmacopoeial impurity reference standard (molecular formula C20H28ClN5, MW 373.92 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Piperaquine Impurity N4 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 373.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H28ClN5 |
| Molecular Weight | 373.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Piperaquine Standards
- Piperaquine Impurity N1 (CAS 4038-99-7)
- Piperaquine Impurity 6 (CAS CATO-C4X-23376)
- Piperaquine Impurity 9 (CAS 1233345-93-1)
- Piperaquine impurity 7 (CAS CATO-C4X-23377)
- Piperaquine Impurity 3 (CAS CATO-C4X-23373)
- Piperaquine Impurity 10 (CAS CATO-C4X-233710)
- Piperaquine Impurity 5 (CAS CATO-C4X-23375)
- Piperaquine Base (CAS 4085-31-8)
Recommended Standards
- 2-[2-(4-chlorophenyl)adamantan-2-yl]-1-(morpholin-4-yl)ethan-1-one 400085-09-8 6F-939 (CAS 400085-09-8)
- Prochlorperazine (CAS 58-38-8)
- 3-((4-Chlorobenzyl)thio)-N-(p-tolyl)thiophene-2-carboxamide (CAS 251097-06-0)
- Prochlorperazine EP Impurity C (CAS 1346602-34-3)
- Empagliflozin Impurity 74 (CAS 81058-27-7)
- Citric Acid Impurity 5 (CAS 5949-29-1)
- Edoxaban Impurity 24 (CAS 500572-10-1)
- 1-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole (CAS 1269291-03-3)
- 2,6-Diethoxypyridine (CAS 13472-57-6)
- 1-(Chloromethoxy)-4-ethoxybenzene (CAS 847186-02-1)
- 1-Vinyl-1-methylsila-17-crown-6 (CAS 83890-25-9)
- (1-(2-Chloropyridin-3-yl)cyclopropyl)methanamine (CAS 1060811-88-2)
- Tert-butyl 5-(((trifluoromethyl)sulfonyl)oxy)-3,6-dihydropyridine-1(2H)-carboxylate (CAS 180691-65-0)
- Cyclolinopeptide B (CAS 193139-41-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com