Piperaquine Impurity N1 CAS 4038-99-7
| CAS No. | 4038-99-7 |
| Molecular Formula | C16H19Cl2N3 |
| Molecular Weight | 324.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Piperaquine Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Piperaquine Impurity N1 (CAS 4038-99-7), a pharmacopoeial impurity reference standard (molecular formula C16H19Cl2N3, MW 324.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H19Cl2N3, Piperaquine Impurity N1 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 324.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H19Cl2N3 |
| Molecular Weight | 324.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Piperaquine Standards
- Piperaquine impurity 7 (CAS CATO-C4X-23377)
- Piperaquine Impurity N4 (CAS 4039-00-3)
- Piperaquine Impurity 6 (CAS CATO-C4X-23376)
- Piperaquine Impurity 9 (CAS 1233345-93-1)
- Piperaquine Impurity 3 (CAS CATO-C4X-23373)
- Piperaquine Impurity 10 (CAS CATO-C4X-233710)
- Piperaquine Impurity 5 (CAS CATO-C4X-23375)
- Piperaquine Base (CAS 4085-31-8)
Recommended Standards
- Trazodone Impurity 34 (CAS CATO-C4X-177234)
- 1-(4-Benzylpiperidin-1-yl)-2-bromobutan-1-one (CAS 1119452-42-4)
- Axitinib Impurity 23 (CAS CATO-C4X-107123)
- 1-(4-Benzylpiperidin-1-yl)-2-bromo-2-methylpropan-1-one (CAS 1225839-46-2)
- Valsartan Impurity 67 (CAS 2254485-68-0)
- Thymalfasin Impurity 8 (CAS CATO-C4X-18988)
- Ceftolozane Impurity 18 (CAS CATO-C4X-240618)
- 6-Methoxy-2-methyl-3-(piperidin-2-yl)pyridine (CAS 1270545-45-3)
- 8-Methoxy-1,4-dioxaspiro[4.5]decane-8-carbaldehyde (CAS 2882106-39-8)
- (R)-2-(2-(1,3-Dioxan-2-yl)ethyl)-1-methylpyrrolidine (2R,3R)-2,3-bis(benzyloxy)succinate (CAS 868618-81-9)
- 4-Chloro-N-(1-isopropyl-5,6-dimethyl-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338423-28-2)
- 3-((1-Ethyl-1h-imidazol-2-yl)oxy)propan-1-amine (CAS 1250732-57-0)
- 5-(1-Methyl-1H-pyrazol-4-yl)pyrazin-2-amine (CAS 1490161-85-7)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com