5-Chloro-4-(6-fluoropyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine CAS 916172-48-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-4-(6-fluoropyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine.

5-Chloro-4-(6-fluoropyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 916172-48-0), molecular formula C12H7ClFN3 and molecular weight 247.66 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 5-Chloro-4-(6-fluoropyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 247.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-Chloro-4-(6-fluoropyridin-2-yl)-1H-pyrrolo[2,3-b]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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